Inflammation is the body's protective response against infections and injuries. Auto-inflammation occurs when the body produces an inflammatory response against its own healthy tissues. Learn about the signs and symptoms of inflammation and auto-inflammation.
This page describes how joint inflammation happens and how juvenile idiopathic arthritis can hurt your joints. It also outlines some of the symptoms of arthritis in young people.
Macrophage activation syndrome (MAS) occurs when the immune system is overactivated and causes inflammation. Learn about the signs, causes and treatment of MAS.
Juvenile Enthesitis Related Arthritis is treated with medicines that reduce inflammation of the joints. Learn about the specific drugs used to treat ERA.
Optic neuritis is inflammation of the optic nerve in the eye. It can occur in one eye or both eyes at the same time. Learn about the signs and symptoms of optic neuritis and what to expect.
Find out why arthritis can occur in young people. This page describes how joint inflammation happens, and how juvenile idiopathic arthritis can hurt your joints. It also outlines some of the symptoms of arthritis in young people.
Neuroinflammatory disorders are conditions in which inflammation affects the central nervous system (the brain, spinal cord, and/or optic nerves).
Antibody-mediated neuroinflammatory disorders are conditions where the body’s immune system attacks its own cells in the central nervous system (the brain, spinal cord, and/or optic nerves). Learn about the different types of antibody-mediated neuroinflammatory brain disorders and what the signs and symptoms are for each.
Juvenile enthesitis-related arthritis includes swelling and pain where tendons and ligaments attach to bone. It affects more boys than girls.
Learn about the benefits of providing oral immune therapy to your hospitalized baby using expressed breast milk.
Does your child have autoimmune hepatitis? Learn the facts and how you can help.
Neuroinflammatory disorders are conditions where parts of the central nervous system are affected by inflammation. Learn about inflammation, the different types of neuroinflammatory disorders, how they are treated and how to cope with illness.
Learn about systemic lupus erythematosus (SLE), including diagnosis, treatment and management of lupus.
Information for parents and children with the inflammatory bowel disease, ulcerative colitis.
Learn about transient synovitis in children, or temporary inflammation of the lining of a joint.
Information for parents and children with the inflammatory bowel disease, Crohn's disease.
Systemic juvenile idiopathic arthritis (sJIA) is an autoinflammatory disease that causes swelling in the joints. Discover quick facts about sJIA, including its symptoms.
Information about an inflammatory disease called chronic recurrent multifocal osteomyelitis which causes pain and swelling in the bones.
In children, post-infectious glomerulonephritis is usually caused by inflammation that follows an infection. Learn more about diagnosis and treatment.
A premature baby is susceptible to infection because their immune system is immature. Read more about infections and the immune system of premature babies.
Information for children, adolescents and their families about eosinophilic esophagitis (EoE), a disorder that involves inflammation and swelling of the esophagus.
JIA can occur in young people, up to age 16. Discover the differences in arthritis between young people and adults, how common arthritis is in young people, and how it can affect the joints.
Learn about multisystem inflammatory syndrome in children (MIS-C), a rare syndrome linked to a SARS-CoV-2 infection.
Find out about the use of biologic agents in the treatment of JIA including what biologics are, how they work, safety considerations and side effects, and the biologics that are currently available to treat JIA.
Rheumatic fever can develop when strep throat is not treated fully with antibiotics. Find out about what symptoms children with rheumatic fever experience and how it is treated.
