Periventricular leucomalacia (PVL) is a condition in which decreased blood flow to brain tissue causes it to soften up and
eventually die, leaving behind cysts, or holes, filled with fluid. Over time, these cysts may fuse together and enlarge or
collapse. The affected brain tissue and the nerve fibres that run through it help to control body movement, and their loss
most often affects this ability.
| Mild Periventricular Leucomalacia (PVL) |
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| Periventricular leucomalacia (PVL) is a condition where there is decreased blood flow to brain tissue. In the mild PVL ultrasound,
there is an increased density around the ventricles which is suggestive of injury. Another head ultrasound should be performed
to see if there has been progression.
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Although the brain tissue damage may have occurred before birth, during delivery, or in the immediate days following birth,
the cysts may take several weeks to appear, delaying a definitive diagnosis. Head ultrasound (HUS) is performed regularly
to confirm diagnosis. If cysts are detected, they may appear to resolve themselves over the course of a month or more, but
the longer term damage from PVL will likely not appear until months later. Generally speaking, damage from PVL affects motor
control and may lead to a diagnosis of cerebral palsy.
| Cystic Periventricular Leucomalacia (PVL) |
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| Sometimes there is a progression of from the early changes seen in mild PVL, and cystic PVL develops. Low blood supply causes
brain tissue to soften up and eventually die, leaving behind cysts, or holes, filled with fluid. Over time, these cysts may
fuse together and enlarge or collapse, affecting control of body movement.
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