Treatment of germ cell tumoursTTreatment of germ cell tumoursTreatment of germ cell tumoursEnglishNeurology;OncologyChild (0-12 years);Teen (13-18 years)BrainNervous systemDrug treatment;Non-drug treatmentAdult (19+)NA2009-07-10T04:00:00Z000Flat ContentHealth A-Z<p>This page describes what is involved in the treatment of a germ cell tumour.</p><p>The treatment of germ cell tumours depends on the type of germ cell tumour. Surgery is required for a type of germ cell tumour called mature teratoma. For all other types of germ cell tumours, aggressive surgery is not recommended. The extent of tumour removed does not predict success in treating the tumour.</p><h2>Key points</h2> <ul><li>Surgery is only required for mature teratoma but not for other types of germ cell tumours.</li> <li>Germinomas are very sensitive to chemotherapy and radiation.</li> <li>Non-germinomas are sensitive to chemotherapy but are less sensitive to radiation</li> <li>Both germinoma and non-germinatous germ cell tumours have relatively high treatment success rates.</li></ul>
Traitement des tumeurs des cellules germinalesTTraitement des tumeurs des cellules germinalesTreatment of germ cell tumoursFrenchNeurology;OncologyChild (0-12 years);Teen (13-18 years)BrainNervous systemDrug treatment;Non-drug treatmentAdult (19+)NA2009-07-10T04:00:00Z000Flat ContentHealth A-Z<p>Dans la présente page, on décrit ce qui joue un rôle dans le traitement de tumeurs des cellules germinales.</p><p>Le traitement des tumeurs des cellules germinales dépend du type de tumeur. La chirurgie est nécessaire pour un type de tumeur des cellules germinales que l’on appelle un tératome mature. Pour tous les autres types de tumeurs des cellules germinales, on ne recommande pas de chirurgie énergique. La quantité de tumeur retirée ne permet pas de prévoir le taux de réussite du traitement de la tumeur.</p><h2>À retenir</h2> <ul><li>Une intervention chirurgicale est nécessaire dans le cas d’un tératome mature, mais pas pour les autres types de tumeurs des cellules germinales.</li> <li>Les germinomes sont très sensibles à la chimiothérapie et à la radiothérapie.</li> <li>Les tumeurs non germinomateuses sont sensibles à la chimiothérapie, mais moins à la radiothérapie.</li> <li>Le taux de réussite des traitements des germinomes et des tumeurs des cellules germinales non germinomateuses est relativement élevé.</li></ul>

 

 

Treatment of germ cell tumours1372.00000000000Treatment of germ cell tumoursTreatment of germ cell tumoursTEnglishNeurology;OncologyChild (0-12 years);Teen (13-18 years)BrainNervous systemDrug treatment;Non-drug treatmentAdult (19+)NA2009-07-10T04:00:00Z000Flat ContentHealth A-Z<p>This page describes what is involved in the treatment of a germ cell tumour.</p><p>The treatment of germ cell tumours depends on the type of germ cell tumour. Surgery is required for a type of germ cell tumour called mature teratoma. For all other types of germ cell tumours, aggressive surgery is not recommended. The extent of tumour removed does not predict success in treating the tumour.</p><h2>Key points</h2> <ul><li>Surgery is only required for mature teratoma but not for other types of germ cell tumours.</li> <li>Germinomas are very sensitive to chemotherapy and radiation.</li> <li>Non-germinomas are sensitive to chemotherapy but are less sensitive to radiation</li> <li>Both germinoma and non-germinatous germ cell tumours have relatively high treatment success rates.</li></ul><h2>How are germ cell tumours treated?</h2><p>Germinomas are very sensitive to chemotherapy and radiation. Non-germinomas are sensitive to chemotherapy but are less sensitive to radiation.</p><p>In North America, the treatment of a germinoma may involve one of the following:</p><ul><li> Craniospinal radiation to the brain and spine </li><li> Focal radiation to the tumour itself </li><li> A combination of chemotherapy and focal radiation </li><li> Chemotherapy only: this protocol is used with caution, as studies using chemotherapy only have been disappointing.</li></ul><p>The treatment of a non-germinatous germ cell tumour or secreting tumour may involve one of the following:</p><ul><li> Chemotherapy and craniospinal radiation </li><li> Chemotherapy and focal radiation </li><li> Chemotherapy only: this protocol is used with caution, as studies using chemotherapy only have been disappointing.</li></ul><p>Surgery may be recommended for non-germinatous germ cell tumours if they do not respond completely to chemotherapy.</p><p>The use of chemotherapy is sometimes complicated in children with diabetes insipidus, particularly when the chemotherapy given requires hydration. This can trigger an imbalance in the fluid electrolytes in the child’s body.</p><p>The testing of tumour markers continues regularly throughout treatment.</p><h2>What is the outcome for a child with a germ cell tumour?</h2><p>The success rate in the treatment of germinoma is more than 90%. Non-germinatous germ cell tumours have a success rate of about 70%.</p><p>For more information, please see:<br></p><ul><li> <a href="/Article?contentid=1317&language=English">Germ Cell Tumours</a></li><li> <a href="/Article?contentid=1331&language=English">Diagnosis of Germ Cell Tumours</a></li> </ul><br>Treatment of germ cell tumours

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