MycophenolateMMycophenolateMycophenolateEnglishPharmacyNANAImmune systemDrugs and SupplementsCaregivers Adult (19+)NA2010-03-17T04:00:00ZRita V. Kutti, BScPhm, RPh58.00000000000009.000000000000001858.00000000000Drugs (A-Z)Drug A-Z<p class="akh-article-overview">Your child needs to take the medicine called mycophenolate. This information sheet explains what mycophenolate does, how to give it, and what side effects or problems your child may have when they take this medicine.</p><p>Your child needs to take the medicine called mycophenolate (say: mye-koe-FEN-oh-late). This information sheet explains what mycophenolate does, how to give it, and what side effects or problems your child may have when they take this medicine. </p><h2>Before giving mycophenolate to your child<br></h2> <p>Talk to your doctor if your child has:</p> <ul><li>ever reacted badly to mycophenolate or any other medication, food, preservative, or colouring agent </li></ul> <h3>Talk with your doctor or pharmacist if your child has any of the following conditions. Precautions may need to be taken with this medication if your child: </h3> <ul><li>has a history of kidney problems or reduced kidney function </li> <li>has a history of stomach or intestine problems </li> <li>has phenylketonuria (PKU) </li> <li>could be pregnant </li></ul><h2>How should you give your child mycophenolate?</h2> <p>Follow these instructions when you give your child mycophenolate by mouth:</p> <ul><li>Give your child mycophenolate exactly as your doctor or your pharmacist tells you to, even if your child seems better. Talk to your child's doctor before you stop giving this medicine for any reason. Your child may become ill if they stop taking this medicine suddenly. </li> <li>Give your child mycophenolate at the same times every day (exactly as your child's doctor or pharmacist tells you). Pick times that are easy for you so that you do not miss doses. </li> <li>Give mycophenolate on an empty stomach (at least one hour before meals or two hours after meals) with a full glass of water, if possible. </li> <li>If your child is taking the tablets or capsules, these should be swallowed whole. Do not cut, crush, or chew them. </li> <li>If your child is taking liquid mycophenolate, shake the bottle very well and then measure the dose with the special spoon or syringe that the pharmacist gave you. </li> <li>Do not mix mycophenolate with other liquids. </li> <li>Wash your hands after giving each dose of mycophenolate. </li> <li>You should avoid inhaling the powder from damaged capsules or tablets. Do not let the powder or liquid touch your skin. </li> <li>Wash the skin well with soap and water if mycophenolate does touch the skin. If it gets in your eyes, rinse with water. If you spill mycophenolate, wipe it up using paper towels wetted with water to remove the powder or liquid. </li></ul> <p>Mycophenolate is also a clear liquid a nurse will give by needle into your child's vein. Your child will get this medicine in the hospital clinic or the nursing unit. </p><h2>What should you do if your child misses a dose of mycophenolate?</h2> <ul><li>Give the missed dose as soon as you remember. </li> <li>If it is almost time for the next dose, skip the missed dose. Give the next dose at the regular time. </li> <li>Do not give your child two doses to make up for one missed dose. </li></ul> <p>If your child throws up within 30 minutes of taking a dose of mycophenolate, repeat the full dose of mycophenolate. If your child throws up more than 30 minutes after a dose, do not give another dose. If your child misses more than one dose, is vomiting or has diarrhea, speak to your doctor or nurse as soon as possible. </p><h2>What are the possible side effects of mycophenolate?</h2> <p>Your child may have some of these side effects while they take mycophenolate. Check with your child's doctor if your child continues to have any of these side effects, and they do not go away, or they bother your child: </p> <ul><li>nausea (upset stomach)? </li> <li>constipation (trouble having a bowel movement) </li> <li>diarrhea (loose stools) </li> <li>heartburn </li> <li>stomach pain </li> <li>mild headache </li> <li>dizziness </li> <li>weakness </li> <li>trouble sleeping </li> <li>acne (pimples) </li></ul> <p>Call your child's doctor during office hours if your child has any of these side effects:</p> <ul><li>vomiting (throwing up) or diarrhea (loose, watery stools) </li> <li>abdominal pain </li> <li>swelling of feet or lower legs </li> <li>redness, swelling, or pain in the gums </li> <li>sores or white patches in the mouth </li> <li>joint or muscle pain </li> <li>skin rash </li></ul> <h3>Most of the following side effects are not common, but they may be a sign of a serious problem. Call your child's doctor right away or take your child to the Emergency Department if your child has any of these side effects:<br></h3> <ul><li>fever or chills </li> <li>cough or sore throat </li> <li>chest pain or shortness of breath </li> <li>fast, irregular, or uneven heart beat </li> <li>throwing up blood or material that looks like coffee grounds </li> <li>blood in urine or stools or dark, tarry stools </li> <li>unusual bleeding or bruising </li> <li>trembling or shaking of the hands or feet<br></li> <li>unusual tiredness or weakness </li> <li>severe headache </li></ul><h2>What safety measures should you take when your child is using mycophenolate?</h2> <p>Keep all appointments at the clinic or doctor's office so that the doctor can check your child's reaction to mycophenolate. The doctor may need to change the dose so that your child is getting the right amount. </p> <p>Your child may have the levels of active mycophenolate (called mycophenolic acid or MPA) in the blood checked from time to time. This is done through blood tests. If your child is to have their levels checked, you may be given special instructions about when to give the doses on the day of this check. </p> <p>As mycophenolate works by lowering the body's natural immunity, your child has an increased risk of getting infections. You can take the following precautions to prevent infections: </p> <ul><li>Keep your child away from people with infections, such as colds or stomach flu. </li> <li>Teach your child to wash their hands. Hand washing is the most important way to prevent the spread of germs that cause infections. </li> <li>Wash your hands before touching your child's eyes, mouth, or the inside of your child's nose. </li></ul> <p>Because mycophenolate lowers the body's immune system, it may increase the risk of developing cancers including skin cancers and lymphomas. The following symptoms are some possible warning signs of cancer. To help detect any cancers as soon as possible, report any of these symptoms to your doctor right away: </p> <ul><li>a change in bowel or bladder habits </li> <li>any sore that does not heal </li> <li>unusual bleeding or discharge </li> <li>the appearance of a lump or thickened areas anywhere on the body </li> <li>unexplained stomach upset or any trouble with swallowing </li> <li>an obvious change in a wart or a mole </li> <li>a nagging cough or hoarseness </li> <li>night sweats </li> <li>persistent and severe headaches </li></ul> <p>As mycophenolate may increase the risk of skin cancer, exposure to the sun should be limited. Your child should use a sun block with an SPF of 15 or higher and protect the skin with clothing when outside for extended periods of time. Your child should avoid tanning beds and sunlamps. </p> <p>Your child should not receive any immunizations (vaccines) without your child's doctor's approval. Your child or anyone else in your household should not get oral polio vaccine while your child is being treated with mycophenolate. Tell your child's doctor if anyone in your household has recently received oral polio vaccine. Your child should avoid contact with anyone who has recently received this vaccine. Other live vaccines that your child should not get include measles, mumps and rubella (MMR), and chicken pox vaccine. </p> <p>There is a chance that mycophenolate may cause birth defects if it is taken at the time of conception or if it is taken during pregnancy. If your child is sexually active, she should use at least two forms of birth control while receiving mycophenolate. Tell the doctor right away if your child may be pregnant. </p> <p>While your child is taking mycophenolate, good mouth care is important. Talk to your doctor, dentist, or pharmacist about what special steps should be taken to keep the mouth clean while using mycophenolate. </p> <p>Check with your child's doctor or pharmacist before giving your child any other medicines (prescription, non-prescription, herbal, or natural products). </p> <p>There are some medicines that should not be taken together with mycophenolate or in some cases the dose of mycophenolate or the other medicine may need to be adjusted. It is important that you tell your doctor and pharmacist if your child takes any other medications including: </p> <ul><li>other immunosuppressants (<a href="/Article?contentid=80&language=English">azathioprine</a>, <a href="/Article?contentid=115&language=English">cyclosporine</a>, <a href="/Article?contentid=244&language=English">tacrolimus</a>) </li> <li>antiviral drugs (<a href="/Article?contentid=65&language=English">acyclovir</a>, <a href="/Article?contentid=146&language=English">ganciclovir</a>) </li> <li><a href="/Article?contentid=98&language=English">cholestyramine</a> </li> <li>oral contraceptives </li></ul><h2>What other important information should you know about mycophenolate?</h2><ul><li>Tell the doctor or dentist that your child is taking mycophenolate before your child has any kind of operation, even on the teeth, or an emergency treatment. </li><li>Although it is preferred that mycophenolate be given without food (on an empty stomach), some children will need to take it with some food to decrease irritation of the stomach. If your child needs to take their mycophenolate with food, always give this medicine to your child with food. </li><li>Avoid giving mycophenolate at the same time as antacids (such as Maalox, Diovol, and Tums), <a href="/Article?contentid=179&language=English">magnesium</a> or other supplements. These may reduce the amount of mycophenolate absorbed into the body. Separate the dose times of these medications from mycophenolate by about two hours. </li><li>Liquid mycophenolate contains aspartame, a source of phenylalanine, and should not be used if your child has phenylketonuria (PKU).<br></li><li>Keep a list of all medications your child is on and show the list to the doctor or pharmacist.</li><li>Do not share your child's medicine with others and do not give anyone else's medicine to your child.</li><li>Make sure you always have enough mycophenolate to last through weekends, holidays, and vacations. Call your pharmacy at least two days before your child runs out of medicine to order refills. Not all pharmacies will carry this medication. </li><li>Keep mycophenolate at room temperature in a cool, dry place away from sunlight. Do not store it in the bathroom or kitchen.</li><li>Liquid mycophenolate is good for 60 days once it is mixed. It should be stored in a glass bottle.</li><li>Do not keep any medicines that are out of date. Check with your pharmacist about the best way to throw away outdated or leftover medicines.<br></li></ul>
MycophénolateMMycophénolateMycophenolateFrenchPharmacyNANAImmune systemDrugs and SupplementsCaregivers Adult (19+)NA2009-08-20T04:00:00ZRita V. Kutti, BScPhm, RPh58.00000000000009.000000000000000Drugs (A-Z)Drug A-Z<p>Votre enfant doit prendre un médicament qui se nomme « mycophénolate ». La présente fiche de renseignements explique comment agit le mycophénolate.</p><p>Votre enfant doit prendre un médicament qui se nomme « mycophénolate ». La présente fiche de renseignements explique comment agit le mycophénolate, comment l'administrer et quels effets secondaires ou quels problèmes pourrait ressentir votre enfant pendant qu'il prend ce médicament. </p><h2>Avant de donner ce médicament à votre enfant</h2> <p>Avisez le médecin si votre enfant :</p> <ul><li>a déjà mal réagi au mycophénolate ou à tout autre médicament, aliment, agent de conservation ou colorant alimentaire naturel. </li></ul> <h3>Avisez votre médecin ou votre pharmacien si votre enfant souffre de l'une des affections suivantes. Il pourrait s'avérer nécessaire de prendre des précautions avec ce médicament si votre enfant : </h3> <ul><li>a des antécédents de problèmes rénaux ou s'il souffre d'une fonction rénale réduite;</li> <li>a des antécédents de problèmes gastriques ou intestinaux;</li> <li>souffre de phénylcétonurie (PCU); </li> <li>pourrait être enceinte. </li></ul><h2>Comment administrer ce médicament à votre enfant</h2> <p>Suivez les instructions suivantes pour donner du mycophénolate par voie orale à votre enfant :</p> <ul><li>Administrez le mycophénolate exactement comme le médecin ou le pharmacien vous a dit de le faire, même si votre enfant semble se porter mieux. Parlez au médecin de votre enfant avant de cesser ce médicament pour quelque raison que ce soit. Votre enfant pourrait tomber malade s'il cesse de prendre ce médicament tout d'un coup. </li> <li>Administrez le mycophénolate aux mêmes heures tous les jours (exactement comme vous l'a indiqué le médecin de votre enfant ou le pharmacien). Choisissez un moment dont vous vous souviendrez facilement afin de ne manquer aucune dose. </li> <li>Administrez le mycophénolate alors que l'estomac de votre enfant est vide (au moins 1 heure avant les repas ou 2 heures après les repas) avec un grand verre d'eau, si possible. </li> <li>Si votre enfant prend les comprimés ou les capsules, il faut les avaler sans les couper, les écraser ou les mâcher. </li> <li>Si votre enfant prend du mycophénolate liquide, agitez bien la bouteille et mesurez la dose à l'aide de la cuillère ou de la seringue spéciale que le pharmacien vous a donnée. </li> <li>Ne mélangez pas le mycophénolate avec d'autres liquides. </li> <li>Lavez bien vos mains après avoir donné une dose de mycophénolate. </li> <li>Évitez d'inhaler la poudre qui pourrait émaner des capsules ou des comprimés endommagés. Ne laissez pas la poudre toucher votre peau. </li> <li>Si le mycophénolate a touché la peau, lavez bien la peau avec de l'eau et du savon. S'il est entré en contact avec les yeux, rincez-les avec de l'eau. Si vous renversez du mycophénolate, essuyez-le avec des essuie-tout imbibés d'eau afin d'essuyer la poudre ou le liquide. </li></ul> <p>Le mycophénolate est également disponible sous forme d'un liquide clair qu'une infirmière peut injecter dans l'une des veines de votre enfant. On administrera ce médicament à la clinique de l'hôpital ou à l'unité des soins. </p><h2>Que faire si votre enfant manque une dose?</h2> <ul><li>Donnez-lui la dose manquée dès que vous y pensez. </li> <li>S'il est presque l'heure de la prochaine dose, sautez la dose manquée. Donnez-lui la prochaine dose à l'heure habituelle. </li> <li>Ne donnez pas 2 doses à votre enfant afin de compenser pour la dose manquée. </li></ul> <p>Si votre enfant vomit dans les 30 minutes qui suivent la dose de mycophénolate, donnez-lui une autre dose complète de mycophénolate. Si votre enfant vomit plus de 30 minutes après la dose, ne lui donnez pas une autre dose. Si votre enfant manque plus d'une dose, s'il a des vomissements ou de la diarrhée, parlez avec votre médecin ou votre infirmière dès que possible. </p><h2>Quels sont les effets secondaires possibles de ce médicament?</h2> <p>Votre enfant pourrait éprouver certains des effets secondaires suivants pendant qu'il prend du mycophénolate. Consultez le médecin de votre enfant si ce dernier affiche un ou plusieurs des effets secondaires suivants et si ces effets ne se résorbent pas ou s'ils dérangent votre enfant : </p> <ul><li>Nausée (maux de cœur) </li> <li>Constipation (difficulté à aller à la selle) </li> <li>Diarrhée (selles liquides) </li> <li>Brûlures d'estomac </li> <li>Douleurs gastriques </li> <li>Légers maux de tête </li> <li>Étourdissements </li> <li>Faiblesse </li> <li>Difficulté à dormir </li> <li>Acné (boutons) </li></ul> <p>Téléphonez au médecin de votre enfant pendant les heures de bureau si votre enfant affiche un ou plusieurs des effets secondaires suivants :</p> <ul><li>Vomissements ou diarrhée (selles molles et aqueuses) </li> <li>Douleurs abdominales</li> <li>Enflure des pieds ou du bas des jambes </li> <li>Gencives rouges, enflées ou douloureuses</li> <li>Plaies ou plaques blanches dans la bouche</li> <li>Douleur articulaire ou musculaire</li> <li>Éruption cutanée </li></ul> <h3>La plupart des effets secondaires suivants ne sont pas courants et pourraient laisser présager un problème grave. Téléphonez immédiatement au médecin de votre enfant ou rendez-vous à la salle d'urgence avec votre enfant si ce dernier affiche l'un des effets secondaires suivants : </h3> <ul><li>Fièvre ou frissons</li> <li>Toux ou mal de gorge</li> <li>Oppression thoracique ou souffle court </li> <li>Fréquence cardiaque rapide, irrégulière ou inégale</li> <li>Vomir du sang ou une substance qui ressemble à des marcs de café</li> <li>Sang dans l'urine ou dans les selles ou selles noires et poisseuses</li> <li>Saignements ou bleus inhabituels</li> <li>Tremblements dans les mains ou les pieds</li> <li>Fatigue ou faiblesse inhabituelle </li> <li>Mal de tête aigu </li></ul><h2>Mesures de sécurité à prendre lorsque votre enfant utilise ce médicament</h2> <p>Conservez tous les rendez-vous à la clinique ou au bureau du médecin afin que ce dernier puisse évaluer comment votre enfant réagit au mycophénolate. Il se peut que le médecin ajuste la dose afin que votre enfant reçoive une quantité adéquate de mycophénolate. </p> <p>Il se peut que l'on vérifie les niveaux de mycophénolate actif (ce que l'on nomme « acide mycophénolique » ou « MPA ») dans le sang de temps à autre, au moyen d'analyses sanguines. Si l'on doit vérifier les niveaux de votre enfant, il se peut que l'on vous donne des instructions spéciales quant au moment approprié pour donner les doses de mycophénolate le jour où l'on doit faire une prise de sang. </p> <p>Puisque le mycophénolate diminue l'immunité naturelle du corps, votre enfant sera plus susceptible de contracter une infection. Voici les précautions à prendre pour prévenir les infections : </p> <ul><li>Évitez les personnes qui ont contracté une infection, comme le rhume ou la grippe. </li> <li>Évitez les endroits bondés. </li> <li>Vous et votre enfant devriez laver vos mains avant de toucher ses yeux ou l'intérieur de son nez. </li></ul> <p>Puisque le mycophénolate affaiblit le système immunitaire, il peut augmenter les risques de développer certains cancers, comme les cancers de la peau et les lymphomes. Les symptômes suivants sont des signes possibles de cancer. Afin de détecter tout cancer le plus rapidement possible, communiquez avec le médecin si votre enfant affiche l'un des symptômes suivants :</p> <ul><li>Altération des selles ou des mictions (uriner)</li> <li>Plaie qui ne guérit pas</li> <li>Saignements ou écoulements inhabituels</li> <li>Apparition d'une bosse ou de parties plus dures sur le corps</li> <li>Maux d'estomac inexpliqués ou difficulté à avaler</li> <li>Modification manifeste d'une verrue ou d'un grain de beauté</li> <li>Une toux persistante ou une voie enrouée</li> <li>Sueurs nocturnes </li> <li>Maux de tête persistants et aigus </li></ul> <p>Puisque le mycophénolate peut augmenter les risques de développer un cancer de la peau, on recommande de limiter l'exposition au soleil. Votre enfant devrait utiliser un écran solaire avec un FPS de 15 ou plus et protéger sa peau avec des vêtements lorsqu'il est à l'extérieur pendant des périodes prolongées. Votre enfant devrait éviter les lits de bronzage et les lampes solaires. </p> <p>Votre enfant ne devrait pas recevoir des immunisations (vaccins) sans l'approbation préalable de son médecin. Votre enfant et tous les membres de votre maisonnée devraient éviter de recevoir le vaccin oral contre la polio (vaccin antipoliomyélitique oral) pendant que votre enfant reçoit des soins contre le cancer. Avisez le médecin de votre enfant si l'un des membres de votre maisonnée a récemment reçu le vaccin antipoliomyélitique oral. Votre enfant devrait éviter d'entrer en contact avec toute personne qui a récemment reçu ce vaccin. De plus, votre enfant ne devrait pas recevoir le vaccin Rougeole-Oreillons-Rubéole (ROR) et le vaccin contre la varicelle, lesquels sont également des vaccins actifs. </p> <p>Le mycophénolate pourrait provoquer des anomalies congénitales si ce médicament est pris au moment de la conception ou au cours de la grossesse. Si votre enfant est sexuellement actif, il devrait utiliser aux moins 2 méthodes de contraception pendant qu'il prend du mycophénolate. Informez votre médecin immédiatement si vous croyez que votre fille pourrait être enceinte. </p> <p>Lorsque votre enfant prend du mycophénolate, une bonne hygiène buccale est de mise. Parlez à votre médecin, au dentiste ou au pharmacien afin d'obtenir des renseignements sur les mesures particulières à prendre pour assurer une bonne hygiène buccale pendant la prise de mycophénolate. </p> <p>Consultez le médecin de votre enfant ou le pharmacien avant de donner tout autre médicament à votre enfant (médicaments sur ordonnance, médicaments sans ordonnance, produits à base d'herbes médicinales ou produits naturels). </p> <p>Certains médicaments ne devraient pas être pris en même temps que le mycophénolate ou, dans certains cas, il pourrait s'avérer nécessaire d'ajuster la dose le mycophénolate ou celle de l'autre médicament. Il est important d'informer votre médecin et votre pharmacien de tout autre médicament que prend votre enfant, y compris : </p> <ul><li>tout autre immunodépresseur (azathioprine, cyclosporine, tacrolimus); </li> <li>des médicaments antiviraux (acyclovir, ganciclovir); </li> <li>de la cholestyramine; </li> <li>des contraceptifs oraux.</li></ul><h2>Autres renseignements importants au sujet de ce médicament</h2><ul><li>Informez le médecin ou le dentiste que votre enfant prend du mycophénolate avant que votre enfant subisse une chirurgie, y compris une chirurgie dentaire, ou qu'il reçoive des soins d'urgence. </li><li>Bien qu'il soit préférable de prendre le mycophénolate sans nourriture (alors que l'estomac de votre enfant est vide), certains enfants devront le prendre avec de la nourriture pour réduire l'irritation de l'estomac. Si votre enfant doit prendre le mycophénolate avec de la nourriture, donnez toujours ce médicament avec de la nourriture. </li><li>Évitez de donner le mycophénolate en même temps que des antiacides (comme du Maalox, du Diovol et des Tums<span id="ms-rterangecursor-start" aria-hidden="true"></span><span id="ms-rterangecursor-end" aria-hidden="true"></span>), du magnésium ou d'autres suppléments. Ces derniers pourraient réduire l'absorption du mycophénolate dans le corps. Prévoyez un intervalle d'environ 2 heures entre ces médicaments et la dose de mycophénolate. </li><li>Le mycophénolate liquide contient de l'aspartame, une source de phénylalanine. Ce médicament n'est pas recommandé si votre enfant souffre de phénylcétonurie (PCU). </li><li>Dressez une liste de tous les médicaments que prend votre enfant et présentez-la au médecin ou au pharmacien.</li><li>Ne partagez pas les médicaments de votre enfant avec d'autres personnes et ne donnez jamais les médicaments d'une autre personne à votre enfant. </li><li>Assurez-vous de toujours avoir des réserves suffisantes de mycophénolate pour les fins de semaine, les congés et les vacances. Téléphonez à la pharmacie pour renouveler votre prescription au moins 2 jours avant d'avoir épuisé tous les médicaments. Certaines pharmacies n'en ont pas. </li><li>Conservez le mycophénolate à température ambiante dans un endroit frais, sec et à l'abri des rayons du soleil. Ne le conservez pas dans la salle de bain ou la cuisine.</li><li>Le mycophénolate liquide est bon pendant 60 jours une fois qu'il est mélangé. Conservez-le dans un contenant de verre. </li><li>Ne conservez pas les médicaments périmés. Demandez à votre pharmacien quelle est la meilleure façon de disposer des médicaments périmés ou excédentaires.<br></li></ul>

 

 

Mycophenolate195.000000000000MycophenolateMycophenolateMEnglishPharmacyNANAImmune systemDrugs and SupplementsCaregivers Adult (19+)NA2010-03-17T04:00:00ZRita V. Kutti, BScPhm, RPh58.00000000000009.000000000000001858.00000000000Drugs (A-Z)Drug A-Z<p class="akh-article-overview">Your child needs to take the medicine called mycophenolate. This information sheet explains what mycophenolate does, how to give it, and what side effects or problems your child may have when they take this medicine.</p><p>Your child needs to take the medicine called mycophenolate (say: mye-koe-FEN-oh-late). This information sheet explains what mycophenolate does, how to give it, and what side effects or problems your child may have when they take this medicine. </p><h2>What is mycophenolate?</h2> <p>Mycophenolate is a medicine called an immunosuppressant. An immunosuppressant reduces the body's immune response. It is used to prevent rejection of transplanted organs, such as the kidney, heart, and liver. It also helps prevent graft versus host disease (GVHD) in bone marrow and stem cell transplant patients. Mycophenolate may also be used to treat other conditions. </p> <p>You may hear mycophenolate called mycophenolate mofetil, MMF, or by its brand name, Cellcept. Mycophenolate comes in capsule, tablet, liquid, and injection forms. </p><h2>Before giving mycophenolate to your child<br></h2> <p>Talk to your doctor if your child has:</p> <ul><li>ever reacted badly to mycophenolate or any other medication, food, preservative, or colouring agent </li></ul> <h3>Talk with your doctor or pharmacist if your child has any of the following conditions. Precautions may need to be taken with this medication if your child: </h3> <ul><li>has a history of kidney problems or reduced kidney function </li> <li>has a history of stomach or intestine problems </li> <li>has phenylketonuria (PKU) </li> <li>could be pregnant </li></ul><h2>How should you give your child mycophenolate?</h2> <p>Follow these instructions when you give your child mycophenolate by mouth:</p> <ul><li>Give your child mycophenolate exactly as your doctor or your pharmacist tells you to, even if your child seems better. Talk to your child's doctor before you stop giving this medicine for any reason. Your child may become ill if they stop taking this medicine suddenly. </li> <li>Give your child mycophenolate at the same times every day (exactly as your child's doctor or pharmacist tells you). Pick times that are easy for you so that you do not miss doses. </li> <li>Give mycophenolate on an empty stomach (at least one hour before meals or two hours after meals) with a full glass of water, if possible. </li> <li>If your child is taking the tablets or capsules, these should be swallowed whole. Do not cut, crush, or chew them. </li> <li>If your child is taking liquid mycophenolate, shake the bottle very well and then measure the dose with the special spoon or syringe that the pharmacist gave you. </li> <li>Do not mix mycophenolate with other liquids. </li> <li>Wash your hands after giving each dose of mycophenolate. </li> <li>You should avoid inhaling the powder from damaged capsules or tablets. Do not let the powder or liquid touch your skin. </li> <li>Wash the skin well with soap and water if mycophenolate does touch the skin. If it gets in your eyes, rinse with water. If you spill mycophenolate, wipe it up using paper towels wetted with water to remove the powder or liquid. </li></ul> <p>Mycophenolate is also a clear liquid a nurse will give by needle into your child's vein. Your child will get this medicine in the hospital clinic or the nursing unit. </p><h2>What should you do if your child misses a dose of mycophenolate?</h2> <ul><li>Give the missed dose as soon as you remember. </li> <li>If it is almost time for the next dose, skip the missed dose. Give the next dose at the regular time. </li> <li>Do not give your child two doses to make up for one missed dose. </li></ul> <p>If your child throws up within 30 minutes of taking a dose of mycophenolate, repeat the full dose of mycophenolate. If your child throws up more than 30 minutes after a dose, do not give another dose. If your child misses more than one dose, is vomiting or has diarrhea, speak to your doctor or nurse as soon as possible. </p><h2>What are the possible side effects of mycophenolate?</h2> <p>Your child may have some of these side effects while they take mycophenolate. Check with your child's doctor if your child continues to have any of these side effects, and they do not go away, or they bother your child: </p> <ul><li>nausea (upset stomach)? </li> <li>constipation (trouble having a bowel movement) </li> <li>diarrhea (loose stools) </li> <li>heartburn </li> <li>stomach pain </li> <li>mild headache </li> <li>dizziness </li> <li>weakness </li> <li>trouble sleeping </li> <li>acne (pimples) </li></ul> <p>Call your child's doctor during office hours if your child has any of these side effects:</p> <ul><li>vomiting (throwing up) or diarrhea (loose, watery stools) </li> <li>abdominal pain </li> <li>swelling of feet or lower legs </li> <li>redness, swelling, or pain in the gums </li> <li>sores or white patches in the mouth </li> <li>joint or muscle pain </li> <li>skin rash </li></ul> <h3>Most of the following side effects are not common, but they may be a sign of a serious problem. Call your child's doctor right away or take your child to the Emergency Department if your child has any of these side effects:<br></h3> <ul><li>fever or chills </li> <li>cough or sore throat </li> <li>chest pain or shortness of breath </li> <li>fast, irregular, or uneven heart beat </li> <li>throwing up blood or material that looks like coffee grounds </li> <li>blood in urine or stools or dark, tarry stools </li> <li>unusual bleeding or bruising </li> <li>trembling or shaking of the hands or feet<br></li> <li>unusual tiredness or weakness </li> <li>severe headache </li></ul><h2>What safety measures should you take when your child is using mycophenolate?</h2> <p>Keep all appointments at the clinic or doctor's office so that the doctor can check your child's reaction to mycophenolate. The doctor may need to change the dose so that your child is getting the right amount. </p> <p>Your child may have the levels of active mycophenolate (called mycophenolic acid or MPA) in the blood checked from time to time. This is done through blood tests. If your child is to have their levels checked, you may be given special instructions about when to give the doses on the day of this check. </p> <p>As mycophenolate works by lowering the body's natural immunity, your child has an increased risk of getting infections. You can take the following precautions to prevent infections: </p> <ul><li>Keep your child away from people with infections, such as colds or stomach flu. </li> <li>Teach your child to wash their hands. Hand washing is the most important way to prevent the spread of germs that cause infections. </li> <li>Wash your hands before touching your child's eyes, mouth, or the inside of your child's nose. </li></ul> <p>Because mycophenolate lowers the body's immune system, it may increase the risk of developing cancers including skin cancers and lymphomas. The following symptoms are some possible warning signs of cancer. To help detect any cancers as soon as possible, report any of these symptoms to your doctor right away: </p> <ul><li>a change in bowel or bladder habits </li> <li>any sore that does not heal </li> <li>unusual bleeding or discharge </li> <li>the appearance of a lump or thickened areas anywhere on the body </li> <li>unexplained stomach upset or any trouble with swallowing </li> <li>an obvious change in a wart or a mole </li> <li>a nagging cough or hoarseness </li> <li>night sweats </li> <li>persistent and severe headaches </li></ul> <p>As mycophenolate may increase the risk of skin cancer, exposure to the sun should be limited. Your child should use a sun block with an SPF of 15 or higher and protect the skin with clothing when outside for extended periods of time. Your child should avoid tanning beds and sunlamps. </p> <p>Your child should not receive any immunizations (vaccines) without your child's doctor's approval. Your child or anyone else in your household should not get oral polio vaccine while your child is being treated with mycophenolate. Tell your child's doctor if anyone in your household has recently received oral polio vaccine. Your child should avoid contact with anyone who has recently received this vaccine. Other live vaccines that your child should not get include measles, mumps and rubella (MMR), and chicken pox vaccine. </p> <p>There is a chance that mycophenolate may cause birth defects if it is taken at the time of conception or if it is taken during pregnancy. If your child is sexually active, she should use at least two forms of birth control while receiving mycophenolate. Tell the doctor right away if your child may be pregnant. </p> <p>While your child is taking mycophenolate, good mouth care is important. Talk to your doctor, dentist, or pharmacist about what special steps should be taken to keep the mouth clean while using mycophenolate. </p> <p>Check with your child's doctor or pharmacist before giving your child any other medicines (prescription, non-prescription, herbal, or natural products). </p> <p>There are some medicines that should not be taken together with mycophenolate or in some cases the dose of mycophenolate or the other medicine may need to be adjusted. It is important that you tell your doctor and pharmacist if your child takes any other medications including: </p> <ul><li>other immunosuppressants (<a href="/Article?contentid=80&language=English">azathioprine</a>, <a href="/Article?contentid=115&language=English">cyclosporine</a>, <a href="/Article?contentid=244&language=English">tacrolimus</a>) </li> <li>antiviral drugs (<a href="/Article?contentid=65&language=English">acyclovir</a>, <a href="/Article?contentid=146&language=English">ganciclovir</a>) </li> <li><a href="/Article?contentid=98&language=English">cholestyramine</a> </li> <li>oral contraceptives </li></ul><h2>What other important information should you know about mycophenolate?</h2><ul><li>Tell the doctor or dentist that your child is taking mycophenolate before your child has any kind of operation, even on the teeth, or an emergency treatment. </li><li>Although it is preferred that mycophenolate be given without food (on an empty stomach), some children will need to take it with some food to decrease irritation of the stomach. If your child needs to take their mycophenolate with food, always give this medicine to your child with food. </li><li>Avoid giving mycophenolate at the same time as antacids (such as Maalox, Diovol, and Tums), <a href="/Article?contentid=179&language=English">magnesium</a> or other supplements. These may reduce the amount of mycophenolate absorbed into the body. Separate the dose times of these medications from mycophenolate by about two hours. </li><li>Liquid mycophenolate contains aspartame, a source of phenylalanine, and should not be used if your child has phenylketonuria (PKU).<br></li><li>Keep a list of all medications your child is on and show the list to the doctor or pharmacist.</li><li>Do not share your child's medicine with others and do not give anyone else's medicine to your child.</li><li>Make sure you always have enough mycophenolate to last through weekends, holidays, and vacations. Call your pharmacy at least two days before your child runs out of medicine to order refills. Not all pharmacies will carry this medication. </li><li>Keep mycophenolate at room temperature in a cool, dry place away from sunlight. Do not store it in the bathroom or kitchen.</li><li>Liquid mycophenolate is good for 60 days once it is mixed. It should be stored in a glass bottle.</li><li>Do not keep any medicines that are out of date. Check with your pharmacist about the best way to throw away outdated or leftover medicines.<br></li></ul>https://assets.aboutkidshealth.ca/AKHAssets/ICO_DrugA-Z.pngMycophenolateMycophenolate

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