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Hypopituitarism in childrenHHypopituitarism in childrenHypopituitarism in childrenEnglishEndocrinologyChild (0-12 years);Teen (13-18 years)BrainEndocrine systemConditions and diseasesAdult (19+) CaregiversNA2022-11-15T05:00:00Z11.000000000000042.20000000000001108.00000000000Flat ContentHealth A-Z<p>Hypopituitarism is a condition that affects hormone development. Learn about the role hormones play in the body, the types of hypopituitarism and how it will impact your child's life.</p><h2>What is hypopituitarism?</h2><p>Hormones are chemicals produced in the body. They act as messengers that travel to other parts of the body where they affect how organs work. Hypopituitarism is a condition where the <a href="/body/interactive?module=brain-child">pituitary gland</a> does not produce one or more pituitary hormones, or it does not produce enough hormones. "Hypo" means less than usual. The term "panhypopituitarism" means many or all of these hormones are deficient ("pan" means all). </p> <figure class="asset-c-80"><img src="https://assets.aboutkidshealth.ca/AKHAssets/Pituitary_gland.jpg" alt="brain showing location of hypothalamus and pituitary gland with close up of anterior and posterior lobes" /><figcaption class="asset-image-caption">Hormones are produced in the pituitary gland and carried to other parts of the body.</figcaption> </figure> <p>The pituitary is a pea-sized gland located in the middle of the skull. It is part of the body’s endocrine system, which includes all the glands that produce and regulate hormones. The pituitary gland acts as the control centre for other glands. Hormones produced in the pituitary gland impact many other parts of the body. The pituitary releases various hormones in response to chemical messages it receives from the part of the brain called the hypothalamus.</p><h2>Key points</h2><ul><li>Hypopituitarism occurs when the pituitary gland does not produce one or more pituitary hormones, or it does not produce enough hormones. </li><li>Hypopituitarism can be congenital (present at birth) or acquired through damage to the pituitary or hypothalamus.</li><li>Types of hypopituitarism include growth hormone deficiency, gonadotropin deficiency, thyroid stimulating hormone deficiency, adrenocorticotrophic hormone deficiency, antidiuretic hormone deficiency and prolactin deficiency.</li><li>Hypopituitarism cannot be prevented but with a good understanding of the condition, correct hormone replacement and regular clinic visits, children can live healthy lives.</li><li>After age 18, children with hypopituitarism will be transitioned to an adult endocrinologist for ongoing care.</li></ul>

 

 

EndocrinologyEndocrinologyEndocrinologyEEnglishEndocrinologyChild (0-12 years);Teen (13-18 years)NAEndocrine systemConditions and diseasesAdult (19+) CaregiversNALanding PageLearning Hub<p>Learn about endocrine disorders including disorders affecting growth, bones, the thyroid, and puberty. The pages below discuss different endocrine disorders affecting children and teens, diagnosis, treatments and how to manage life-long conditions.</p><p>Learn about endocrine disorders including disorders affecting growth, bones, the thyroid, and puberty. The pages below discuss different endocrine disorders affecting children and teens, diagnosis, treatments and how to manage life-long conditions.</p><div class="panel panel-primary"><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h2 class="panel-title">Adrenal</h2></div><div class="panel-body list-group" style="display:none;"><p>The adrenal glands are small, triangular-shaped glands located on top of both kidneys. Learn about conditions of the adrenal glands including congenital adrenal hyperplasia, adrenal insufficiency and Addison's disease.</p></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="http://www.bcchildrens.ca/endocrinology-diabetes-site/Documents/cahbooklet.pdf">Congenital adrenal hyperplasia booklet</a></li><li class="list-group-item"><a class="overview-links" href="https://pedsendo.org/patient-resource/adrenal-insufficiency/">Adrenal insufficiency: A guide for families</a></li><li class="list-group-item"><a class="overview-links" href="https://www.sickkids.ca/siteassets/care--services/clinical-departments/endocrinology/how-to-give-florinef-to-babies.pdf">How to give florinef to babies</a></li><li class="list-group-item"><a class="overview-links" href="https://assets.aboutkidshealth.ca/AKHAssets/Hydrocortisone%20suspension.pdf">Hydrocortisone suspension</a></li><li class="list-group-item"><a class="overview-links" href="https://www.magicfoundation.org/Downloads/Cushing%20Syndrome%20in%20Childhood.pdf">Cushing's syndrome</a></li><li class="list-group-item"><a class="overview-links" href="http://www.addisonsociety.ca/pdfs/cas-brochure.pdf">Addison's disease</a></li><li class="list-group-item"><a class="overview-links" href="/body/interactive?module=sex-development">How the body works: Sex development</a></li></ol></div><div class="panel panel-primary"><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h2 class="panel-title">Calcium parathyroid & bone</h2></div><div class="panel-body list-group" style="display:none;"><p>Read about the importance of bone health for children, conditions that affect the bones and how they can be managed.</p></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="https://www.bones.nih.gov/health-info/bone/bone-health/juvenile">Kids and their bones: A guide for parents</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=1970&language=English">Bone health: The role of calcium and vitamin D</a></li><li class="list-group-item"><a class="overview-links" href="http://www.bcchildrens.ca/endocrinology-diabetes-site/documents/vitdrickets.pdf">Vitamin D deficiency and rickets</a></li><li class="list-group-item"><a class="overview-links" href="https://rarediseases.info.nih.gov/diseases/12943/x-linked-hypophosphatemia">X-linked hypophosphatemic rickets (XLH)</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=948&language=English">Osteoporosis: Overview</a></li><li class="list-group-item"><a class="overview-links" href="https://pedsendo.org/patient-resource/hypoparathyroidism/">Hypoparathyroidism</a></li><li class="list-group-item"><a class="overview-links" href="http://www.bcchildrens.ca/endocrinology-diabetes-site/documents/php.pdf">Pseudohypoparathyroidism</a></li><li class="list-group-item"><a class="overview-links" href="https://www.stanfordchildrens.org/en/topic/default?id=hyperparathyroidism-in-children-90-P01958">Hyperparathyroidism</a></li><li class="list-group-item"><a class="overview-links" href="https://www.chop.edu/conditions-diseases/hypocalcemia">Hypocalcemia</a></li><li class="list-group-item"><a class="overview-links" href="https://www.chop.edu/conditions-diseases/hypercalcemia">Hypercalcemia</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=209&language=English">Pamidronate: Informational handout for families</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4175&language=English">Zoledronate: Informational handout for families</a></li></ol></div><div class="panel panel-primary"><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h2 class="panel-title">Growth</h2></div><div class="panel-body list-group" style="display:none;"><p>Children and teens can experience growth problems for several reasons. Learn about growth problems, growth hormone deficiency, short stature and what can be done about these conditions.</p></div><ol class="list-group" style="display:none;"><li><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h3>General</h3></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="/Article?contentid=951&language=English">Growth problems</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=3910&language=English">Virtual care: How to accurately measure your child’s height and weight at home</a></li></ol></li><li><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h3>Growth hormone deficiency</h3></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="https://pedsendo.org/patient-resource/growth-hormone-deficiency/">Growth hormone deficiency: A guide for families</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4164&language=English">Beginning growth hormone therapy: FAQs</a></li></ol></li><li><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h3>Short stature (small for gestational age & growth)</h3></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="https://pedsendo.org/patient-resource/short-stature/">Short stature: A guide for families</a></li><li class="list-group-item"><a class="overview-links" href="https://pedsendo.org/patient-resource/growth-in-babies-born-small-for-gestational-age/">Growth in babies born small for gestational age: A guide for families</a></li></ol></li></ol></div><div class="panel panel-primary"><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h2 class="panel-title">Hypoglycemia & hyperinsulinism</h2></div><div class="panel-body list-group" style="display:none;"><p>Learn about hypoglycemia and hyperinsulinism, how they impact blood sugar levels, and how they can be managed.</p></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4185&language=English">Hypoglycemia in infants and children with hyperinsulinism</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4200&language=English">Diazoxide</a></li><li class="list-group-item"><a class="overview-links" href="https://www.sickkids.ca/siteassets/care--services/clinical-departments/endocrinology/how-to-give-an-emergency-glucagon-injection.pdf">How to give emergency glucagon</a></li><li class="list-group-item"><a class="overview-links" href="https://www.sickkids.ca/siteassets/care--services/clinical-departments/endocrinology/instructions-for-the-emergency-department.pdf">Hyperinsulinism: Emergency care plan for a hypoglycemic episode</a></li></ol></div><div class="panel panel-primary"><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h2 class="panel-title">Pituitary</h2></div><div class="panel-body list-group" style="display:none;"><p>The pituitary gland makes several important hormones. Find out which endocrine disorders affect the pituitary gland and how they can be managed.</p></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4085&language=English">Hypopituitarism</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4089&language=English">Adrenocorticotrophic hormone (ACTH) deficiency</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4090&language=English">Antidiuretic hormone (ADH) deficiency</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4091&language=English">Gonadotropin (FSH, LH) deficiency</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4093&language=English">Thyroid stimulating hormone (TSH) deficiency</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4092&language=English">Growth hormone (GH) deficiency</a></li><li class="list-group-item"><a class="overview-links" href="https://pedsendo.org/patient-resource/growth-hormone-deficiency/">Growth hormone deficiency: A guide for families</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4164&language=English">Beginning growth hormone therapy: FAQs</a></li><li class="list-group-item"><a class="overview-links" href="https://www.chop.edu/conditions-diseases/septo-optic-dysplasia">Septo-optic dysplasia</a></li></ol></div><div class="panel panel-primary"><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h2 class="panel-title">Puberty</h2></div><div class="panel-body list-group" style="display:none;"><p>There are several conditions that can impact puberty. Other conditions may not occur until your child enters puberty. Learn more about puberty and conditions that can affect it.</p></div><ol class="list-group" style="display:none;"><li><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h3>General</h3></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="https://youngwomenshealth.org/2010/04/21/puberty/">Puberty: Girls</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=623&language=English">Puberty in girls</a></li><li class="list-group-item"><a class="overview-links" href="https://youngmenshealthsite.org/guides/puberty/">Puberty: Boys</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=624&language=English">Puberty in boys</a></li><li class="list-group-item"><a class="overview-links" href="https://www.chop.edu/conditions-diseases/hypogonadism">Low production of sex hormones (hypogonadism)</a></li><li class="list-group-item"><a class="overview-links" href="https://kidshealth.org/en/teens/boybrst.html">Breast tissue in boys (gynecomastia)</a></li></ol></li><li><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h3>Early puberty</h3></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="https://pedsendo.org/patient-resource/precocious-puberty/">Early puberty</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=171&language=English">Leuprolide (Lupron)</a></li></ol></li><li><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h3>Delayed puberty</h3></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="https://pedsendo.org/patient-resource/delayed-puberty-girls/">Delayed puberty in girls</a></li><li class="list-group-item"><a class="overview-links" href="https://pedsendo.org/patient-resource/delayed-puberty-boys/">Delayed puberty in boys</a></li></ol></li><li><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h3>Polycystic ovary syndrome (PCOS)</h3></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="/Article?contentid=10&language=English">Polycystic ovary syndrome (PCOS)</a></li><li class="list-group-item"><a class="overview-links" href="https://youngwomenshealth.org/2014/02/25/polycystic-ovary-syndrome/">Polycystic ovary syndrome (PCOS): General information</a></li></ol></li></ol></div><div class="panel panel-primary"><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h2 class="panel-title">Thyroid</h2></div><div class="panel-body list-group" style="display:none;"><p>The thyroid is a butterfly-shaped gland that sits at the front of the neck. Learn about conditions that can affect the thyroid and how they can be managed.</p></div><ol class="list-group" style="display:none;"><li><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h3>General</h3></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="https://www.chop.edu/conditions-diseases/pediatric-thyroid-disorders">Thyroid function, anatomy and hormones</a></li><li class="list-group-item"><a class="overview-links" href="https://thyroid.ca/resource-material/information-on-thyroid-disease/thyroid-disease-in-childhood/">Thyroid disease in childhood</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=2526&language=English">Thyroid disease and diabetes</a></li><li class="list-group-item"><a class="overview-links" href="https://www.sickkids.ca/siteassets/care--services/clinical-departments/endocrinology/how-to-give-l-thyroxine-to-babies-updated-may-2018.pdf">How to give L-thyroxine tablets to babies</a></li><li class="list-group-item"><a class="overview-links" href="https://www.thyroid.org/wp-content/uploads/patients/brochures/pediatric-thyroid-function-tests-brochure.pdf">Pediatric thyroid function tests</a></li></ol></li><li><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h3>Hypothyroidism</h3></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="/Article?contentid=2309&language=English">Hypothyroidism</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4084&language=English">Congenital hypothyroidsim</a></li></ol></li><li><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h3>Hyperthyroidism</h3></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="http://www.bcchildrens.ca/endocrinology-diabetes-site/documents/hyperthyroidbooklet.pdf">Hyperthyroidism booklet created by BC Children's Hospital</a></li><li class="list-group-item"><a class="overview-links" href="https://www.stanfordchildrens.org/en/topic/default?id=hyperthyroidism-graves-disease-90-P01955">Graves disease in a newborn created by Stanford Children's Hospital</a></li><li class="list-group-item"><a class="overview-links" href="https://www.thyroid.org/wp-content/uploads/patients/brochures/hyperthyroidism_children_adolescents_brochure.pdf">Hyperthyroidism in children and adolescents</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4209&language=English">Methimazole</a></li></ol></li><li><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h3>Thyroid nodules and cancer</h3></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="https://www.thyroidcancercanada.org/en/thyroid-cancer/what-is-it">What is thyroid cancer?</a></li><li class="list-group-item"><a class="overview-links" href="https://teens.aboutkidshealth.ca/Article?contentid=3430&language=English&hub=cancer">Thyroid cancer for teens</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=3205&language=English">Thyroid biopsy/FNA using image guidance</a></li><li class="list-group-item"><a class="overview-links" href="https://www.sickkids.ca/siteassets/care--services/clinical-departments/endocrinology/what-to-expect-after-thyroid-biopsy.pdf">What to expect after thyroid biopsy</a></li><li class="list-group-item"><a class="overview-links" href="https://www.sickkids.ca/siteassets/care--services/clinical-departments/endocrinology/what-to-expect-after-surgery-thyroidectomy.pdf">What to expect after surgery (thyroidectomy)</a></li><li class="list-group-item"><a class="overview-links" href="https://www.sickkids.ca/siteassets/care--services/clinical-departments/endocrinology/instructions-for-patients-receiving-radioiodine-therapy.pdf">Instructions for patients receiving radioiodine therapy</a></li><li class="list-group-item"><a class="overview-links" href="https://static1.squarespace.com/static/58ff955aff7c503f699674d7/t/59754ff83a041155fa4a65ce/1500860412769/TCC_LID_Booklet_E_web_2017.pdf">Low iodine diet created by Thyroid Cancer Canada</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4086&language=English">Hypocalcemia: Post-surgical monitoring</a></li><li class="list-group-item"><a class="overview-links" href="https://www.thyroid.org/wp-content/uploads/patients/brochures/thyroid-nodules-children-adolescents-brochure.pdf">Thyroid nodules in children and adolescents</a></li><li class="list-group-item"><a class="overview-links" href="https://www.thyroid.org/wp-content/uploads/patients/brochures/pediatric-differentiated-thyroid-cancer-brochure.pdf">Pediatric differentiated thyroid cancer</a></li></ol></li></ol></div><div class="panel panel-primary"><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h2 class="panel-title">Endocrine disorders after treatment for childhood brain tumours</h2></div><div class="panel-body list-group" style="display:none;"><p>Brain tumours and their treatments can impact the hypothalamus and pituitary gland. As a result, children may need treatment for endocrine disorders. Learn more in the pages below.</p></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="/Article?contentid=1430&language=English">Diabetes insipidus after brain tumour treatment</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=1425&language=English">Thyroid abnormalities after brain tumour treatment</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=1424&language=English">Effects of brain tumours and treatment on growth in childhood</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=1429&language=English">Effects of brain tumours and treatment on the adrenal glands</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=1428&language=English">Puberty and fertility in boys after diagnosis and treatment for brain tumours</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=4014&language=English">Puberty and fertility in girls after diagnosis and treatment for brain tumours</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=1426&language=English">Osteoporosis after brain tumour treatment</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=1427&language=English">Excess weight gain after brain tumour treatment</a></li></ol></div><div class="panel panel-primary"><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h2 class="panel-title">Other endocrine disorders</h2></div><div class="panel-body list-group" style="display:none;"><p>Read about other endocrine disorders that affect children and teens, and find resources from other organizations to help support you and your child.</p></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="https://www.negenetics.org/genetic-education-materials-school-success-gemss">Genetic education materials for school success (GEMSS)</a></li><li class="list-group-item"><a class="overview-links" href="https://www.kidsbonescanada.org/">Kids Bones Canada</a></li><li class="list-group-item"><a class="overview-links" href="https://pedsendo.org/patient-resource/klinefelter-syndrome/">Klinefelter syndrome</a></li><li class="list-group-item"><a class="overview-links" href="https://www.magicfoundation.org/Growth-Disorders/McCune-Albright-Syndrome-or-Fibrous-Dysplasia/">McCune-Albright syndrome</a></li><li class="list-group-item"><a class="overview-links" href="https://www.chop.edu/conditions-diseases/noonan-syndrome">Noonan syndrome</a></li><li class="list-group-item"><a class="overview-links" href="https://www.pwsa.co.uk/">Prader-Willi syndrome</a></li><li class="list-group-item"><a class="overview-links" href="https://www.magicfoundation.org/Growth-Disorders/Russell-Silver-Syndrome/">Russell Silver syndrome</a></li><li class="list-group-item"><a class="overview-links" href="https://www.magicfoundation.org/">The Magic Foundation</a></li><li class="list-group-item"><a class="overview-links" href="https://kidshealth.org/en/parents/turner.html">Turner syndrome</a></li></ol></div><div class="panel panel-primary"><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h2 class="panel-title">Nutrition, physical activity and mental health</h2></div><div class="panel-body list-group" style="display:none;"><p>The Meant2Prevent Resource Hub has trusted youth-focused resources that promote healthy living, mental health and lifestyle habits. Also find resources from AboutKidsHealth on supporting mental health and wellbeing. </p></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="https://meant2prevent.ca/">Meant2Prevent Resource Hub</a></li><li class="list-group-item"><a class="overview-links" href="/mental%20health">Mental Health Learning Hub</a></li><li class="list-group-item"><a class="overview-links" href="/Article?contentid=642&language=English">Physical activity guidelines</a></li><li class="list-group-item"><a class="overview-links" href="/nutrition">Nutrition</a></li></ol></div><div class="panel panel-primary"><div class="panel-heading clickable"> <span class="pull-right panel-heading-collapsable-icon"> <i class="mdi mdi-chevron-down"></i></span><h2 class="panel-title">Diabetes Learning Hub</h2></div><div class="panel-body list-group" style="display:none;"><p>Visit the Diabetes Learning Hub to learn more about type 1 and type 2 diabetes, insulin, and managing your child's care.</p></div><ol class="list-group" style="display:none;"><li class="list-group-item"><a class="overview-links" href="/diabetes">Diabetes Learning Hub</a></li></ol></div>https://assets.aboutkidshealth.ca/AKHAssets/Endocrinology%20learning%20hub.jpgendocrinology

 

 

Hypopituitarism in children4085.00000000000Hypopituitarism in childrenHypopituitarism in childrenHEnglishEndocrinologyChild (0-12 years);Teen (13-18 years)BrainEndocrine systemConditions and diseasesAdult (19+) CaregiversNA2022-11-15T05:00:00Z11.000000000000042.20000000000001108.00000000000Flat ContentHealth A-Z<p>Hypopituitarism is a condition that affects hormone development. Learn about the role hormones play in the body, the types of hypopituitarism and how it will impact your child's life.</p><h2>What is hypopituitarism?</h2><p>Hormones are chemicals produced in the body. They act as messengers that travel to other parts of the body where they affect how organs work. Hypopituitarism is a condition where the <a href="/body/interactive?module=brain-child">pituitary gland</a> does not produce one or more pituitary hormones, or it does not produce enough hormones. "Hypo" means less than usual. The term "panhypopituitarism" means many or all of these hormones are deficient ("pan" means all). </p> <figure class="asset-c-80"><img src="https://assets.aboutkidshealth.ca/AKHAssets/Pituitary_gland.jpg" alt="brain showing location of hypothalamus and pituitary gland with close up of anterior and posterior lobes" /><figcaption class="asset-image-caption">Hormones are produced in the pituitary gland and carried to other parts of the body.</figcaption> </figure> <p>The pituitary is a pea-sized gland located in the middle of the skull. It is part of the body’s endocrine system, which includes all the glands that produce and regulate hormones. The pituitary gland acts as the control centre for other glands. Hormones produced in the pituitary gland impact many other parts of the body. The pituitary releases various hormones in response to chemical messages it receives from the part of the brain called the hypothalamus.</p><h2>Key points</h2><ul><li>Hypopituitarism occurs when the pituitary gland does not produce one or more pituitary hormones, or it does not produce enough hormones. </li><li>Hypopituitarism can be congenital (present at birth) or acquired through damage to the pituitary or hypothalamus.</li><li>Types of hypopituitarism include growth hormone deficiency, gonadotropin deficiency, thyroid stimulating hormone deficiency, adrenocorticotrophic hormone deficiency, antidiuretic hormone deficiency and prolactin deficiency.</li><li>Hypopituitarism cannot be prevented but with a good understanding of the condition, correct hormone replacement and regular clinic visits, children can live healthy lives.</li><li>After age 18, children with hypopituitarism will be transitioned to an adult endocrinologist for ongoing care.</li></ul><figure> <img src="https://assets.aboutkidshealth.ca/AKHAssets/Pituitary_gland_messengers.jpg" alt="image of body showing hormones being carried from pituitary gland to organs through blood vessel" /> <figcaption class="asset-image-caption">Hormones are produced in the pituitary gland and carried to other parts of the body.</figcaption> </figure> <p>The target glands are those glands in the body that make their own hormones in response to hormones received from the pituitary gland. Some of these target glands include:</p><ul><li>the thyroid gland</li><li>the adrenal gland</li><li>the ovaries in females and the testes (or testicles) in males</li></ul><p>Once the hormones are released from the target glands, the bloodstream then carries them to the tissues and organs of the body that use them. For example, hormones produced in the thyroid impact the body’s metabolism, heart rate, temperature, and more.</p><p>The front (anterior) part of the pituitary gland produces several different types of hormones that are needed for the body to function normally. The hormones that come from the anterior pituitary gland are:</p><ul><li>thyroid stimulating hormone (TSH)</li><li>prolactin (PRL)</li><li>adrenocorticotrophic hormone (ACTH)</li><li>luteinizing hormone (LH) </li><li>follicle stimulating hormone (FSH)</li><li>growth hormone (GH)</li></ul> <figure class="asset-c-80"> <img src="https://assets.aboutkidshealth.ca/AKHAssets/Anterior_pituitary_hormones_glands.jpg" alt="anterior pituitary lobe produces TSH, PRL, ACTH, LH, FSH, GH" /> </figure> <p>The back (posterior) part of the pituitary stores the hormones known as antidiuretic hormone (ADH) and oxytocin.</p> <figure class="asset-c-80"> <img src="https://assets.aboutkidshealth.ca/AKHAssets/Posterior_pituitary_hormones_glands.jpg" alt="posterior pituitary lobe produces ADH and oxytocin" /> </figure> <h2>What causes hypopituitarism?</h2><p>In many cases, the cause of hypopituitarism is unknown. However, it is not generally something that is passed on by parents to their children. Hypopituitarism may be:</p><ul><li>Congenital (meaning present at birth) – The pituitary or hypothalamus did not form normally before birth (e.g., septo optic dysplasia).</li><li>Acquired – There was damage to the pituitary or hypothalamus during or sometime after birth.</li></ul><p>A tumour in the pituitary area of the brain, a severe head injury, or a brain infection (such as encephalitis) can result in acquired hypopituitarism. Other causes include surgical removal of the pituitary gland, some chemotherapy, or radiation therapy to the part of the brain where the pituitary is located.</p><h2>What hypopituitarism means to you</h2><p>At this time, your child may be missing one or more pituitary hormones. As a result, it is important for you and your family to have knowledge of ALL the other pituitary hormones, because sometimes children have evolving hypopituitarism (loss of more pituitary hormones over time). Your child’s doctors and nurses will watch for signs and symptoms of additional hormone deficiencies whenever you are seen in clinic. However, we also rely on your observations between visits. Hypopituitarism is almost always a permanent condition, but it is treatable. Treatment involves replacing the hormones normally made by the target glands with hormones your child takes as a pill, injection (needle), or intranasal (in the nose) spray. We will review each hormone separately, and its effect on growth, development, and continued good health.</p><h2>Different types of hormone deficiencies </h2><p>Hypopituitarism may include the following hormone deficiencies: </p><ul><li><a href="/article?contentid=4092&language=english">Growth hormone (GH) deficiency</a>. GH affects the growth of bone, muscle, and other body tissues.</li><li><a href="/article?contentid=4091&language=english">Gonadotropin (FSH, LH) deficiency</a>. Gonadotropins begin the process of sexual development (puberty).</li><li><a href="/article?contentid=4093&language=english">Thyroid stimulating hormone (TSH) deficiency</a>. TSH stimulates the thyroid to produce thyroid hormones, which are important for growth, physical development, brain development, and for normal metabolism of the body.</li><li><a href="/article?contentid=4089&language=english">Adrenocorticotrophic hormone (ACTH) deficiency</a>. ACTH deficiency results in a lack of cortisol, which is a hormone made by the adrenal glands. Cortisol keeps the body’s blood sugar at a normal level and helps the body deal with physical stress, such as fever or injury.</li><li><a href="/article?contentid=4090&language=english">Antidiuretic hormone (ADH) deficiency</a>. ADH helps the body to retain the water that it needs to function properly.</li><li>Prolactin deficiency. Prolactin stimulates breast milk production after childbirth. Prolactin deficiency would not be noted or assessed until after a woman gives birth. There is currently no treatment for prolactin deficiency.</li></ul><h2>Infertility and hypopituitarism </h2><p>For most people with hypopituitarism, just because the pituitary gland may not be fully functioning, it does not mean that the gonads (ovaries or testes) do not work. This will be monitored very closely. When a person with hypopituitarism is ready to have children, they should speak to their health-care provider to make sure their ovaries or testes are healthy. They may need to be referred to a fertility specialist.</p><h2>Psychosocial impact of hypopituitarism</h2><p>You may be faced with many challenges while taking care of a child with a chronic condition. Some challenges that families may face include:</p><ul><li>Learning and mastering new skills and knowledge to care for your child with hypopituitarism.</li><li>Allowing time to accept the diagnosis.</li><li>Financial challenges, particularly if medications are not covered by private insurance plans.</li><li>Frequent clinic visits requiring time off work/school.</li><li>Taking multiple medications and ensuring they are given on time.</li><li>Finding a day care for a child with a chronic condition.</li><li>Teasing or bullying, as children with hypopituitarism may be somewhat delayed as compared to their peers in the areas of growth (height) and development (puberty).</li><li>Potential infertility or the need for assistive reproductive technologies in the future.</li></ul><p>Parents/caregivers may feel guilty or blame themselves for their children’s health issues. It is important to remember that hypopituitarism is not a condition that can be prevented in any way. With a good understanding of hypopituitarism, correct hormone replacement and regular clinic visits, your child can look forward to a healthy life.</p><p>The following resources can also help you to support both your child and you:</p><ul><li> <a href="/article?contentid=3400&language=english">Living with a chronic condition: Overview</a></li><li> <a href="/article?contentid=3401&language=english&hub=mentalhealth">Living with a chronic condition: Helping your child manage their health</a></li><li> <a href="/article?contentid=3402&language=english">Living with a chronic condition: Maintaining your child's everyday routines</a></li><li> <a href="/article?contentid=3403&language=english">Living with a chronic condition: Supporting yourself as a caregiver</a></li></ul><h2>Transitioning to adult care</h2><p>The endocrine team will be there to help you and your child manage their hypopituitarism until they turn 18 years old. After that point, your child will be transitioned to an adult endocrinologist for ongoing follow up. For people who have evolving hypopituitarism, their adult endocrinologist may suggest yearly blood work to monitor pituitary function. Because of the complexity of hypopituitarism, having an involved and collaborative relationship with your adult endocrinologist very important.</p><p>For more information, please see the Transitioning to Adult Care Learning Hub: <a href="/transitionadultcare">https://www.aboutkidshealth.ca/transitionadultcare</a>.</p>Hypopituitarism in childrenFalse

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