ThiotepaTThiotepaThiotepaEnglishPharmacyNANANADrugs and SupplementsCaregivers Adult (19+)NA2010-03-25T04:00:00ZRita V. Kutti, BScPhm, RPh8.1000000000000061.90000000000001208.00000000000Drugs (A-Z)Drug A-Z<p>Your child needs to take the medicine called thiotepa. This information sheet explains what thiotepa does, how to give it, and what side effects or problems your child may have when they take this medicine.</p><p>Your child needs to take the medicine called thiotepa (say: thye-oh-TEE-pah). This information sheet explains what thiotepa does, how to give it, and what side effects or problems your child may have when they take this medicine.</p><h2>Before giving thiotepa to your child</h2> <p>Tell your doctor if your child has ever reacted badly to thiotepa or to any other medications, foods, preservatives, or colouring agents.</p> <h3>Talk with the doctor or pharmacist if your child has any of the following conditions. This medicine may not be right for your child if they have:</h3> <ul><li>an infection or recent exposure to infection (such as chickenpox)</li> <li>kidney or liver problems</li></ul><h2>How will your child get thiotepa?</h2> <p>Thiotepa is a clear liquid that a nurse will give by needle into your child's vein (intravenously or IV). Your child will get this medicine in the hospital clinic or on a nursing unit.</p><h2>What are the possible side effects of thiotepa?</h2> <p>Your child may have some of these side effects while they take thiotepa. Check with your child's doctor if your child continues to have any of these side effects, and they do not go away or they bother your child:</p> <ul><li>dizziness or drowsiness</li> <li>not feeling hungry or loss of appetite</li> <li>nausea (upset stomach) or vomiting (throwing up)</li></ul> <p>Call your child's doctor during office hours if your child has any of these side effects:</p> <ul><li>pain in joints</li> <li>pain at place of injection</li> <li>swelling of feet or lower legs</li> <li>sores in mouth or lips</li></ul> <h3>Most of the following side effects are not common, but they may be a sign of a serious problem. Call your child's doctor right away or take your child to the Emergency Department if your child has any of these side effects:</h3> <ul><li>fever or chills</li> <li>cough or sore throat</li> <li>blood in the urine or stools</li> <li>black, tarry stools</li> <li>pinpoint red spots on skin</li> <li>painful or difficult urination</li> <li>lower back or side pain</li> <li>tightness in the throat</li> <li>wheezing or trouble breathing</li> <li>hives (raised, red itchy areas on the skin)</li> <li>seizures (convulsions)</li></ul><h2>What safety measures should you take when your child is using thiotepa?</h2> <p>Tell the doctor or dentist that your child is taking thiotepa before your child has any operation, even on the teeth, or an emergency treatment.</p> <p>Keep all appointments at the clinic or doctor's office so that the doctor can check your child's reaction to thiotepa.</p> <p>Your child will receive medicine to prevent upset stomach and throwing up caused by thiotepa.</p> <p>Thiotepa may cause sores in the mouth. Rinse your child's mouth with a mouthwash made from baking soda to help keep it clean. Your nurse or pharmacist can review this with you. Avoid store bought mouthwash containing alcohol as it may sting and cause dry mouth.</p> <p>Your child's skin may darken while receiving thiotepa, especially on the elbows and knees and in skin creases. If this happens, it will slowly fade once your child stops taking thiotepa.</p> <p>After treatment with thiotepa, this medicine may come through the skin as part of perspiration (sweat). This can cause irritation of the skin and can cause the skin to change colour. It may also mean that you or your child's caregivers are exposed to small amounts of this drug. As a result, your child's doctor or nurse may suggest:</p> <ul><li>frequent baths while your child is receiving thiotepa: When you are bathing your child, pay particular attention to folds in the skin (such as armpits, groin, elbows, and back of knees). Wash all areas well and pat dry. Avoid rubbing, which may damage the skin.</li> <li>changing your child's clothes or bed linens regularly</li> <li>considering gloves and/or a gown to protect yourself from contact with thiotepa</li></ul> <p>Your child may lose their hair. It will grow back once your child is no longer receiving thiotepa. Its colour and texture may change. Use a gentle shampoo and a soft brush.</p> <p>Thiotepa can lower the number of white blood cells in the blood temporarily, which increases your child's chances of getting an infection. Your child can take the following precautions to prevent infections, especially when the blood count is low:</p> <ul><li>Avoid people with infections, such as a cold or the flu.</li> <li>Avoid places that are very crowded with large groups of people.</li> <li>Be careful when brushing or flossing your child's teeth. Your doctor, nurse, or dentist may suggest different ways to clean your child's mouth and teeth.</li> <li>You and your child should not touch your child's eyes or inside their nose without washing hands first.</li> <li>Your child's nurse will review with you what to do in case of fever.</li></ul> <p>Thiotepa can lower the number of platelets in the blood, which increases your child's risk of bleeding. You can take the following precautions:</p> <ul><li>Be careful not to cut your child when using a razor, fingernail scissors, or toenail clippers.</li> <li>Your child should avoid contact sports where bruising or injury could occur.</li> <li>Before your child has surgery, including dental surgery, inform the doctor or dentist that your child is taking thiotepa.</li> <li>Your child should not receive a permanent tattoo or any kind of body piercing.</li></ul> <p>Your child should not receive any immunizations (vaccines) without your child's doctor's approval. Your child or anyone else in your household should not get oral polio vaccine while your child is being treated for cancer. Tell your child's doctor if anyone in your household has recently received oral polio vaccine. Your child should avoid contact with anyone who has recently received this vaccine.</p> <p>There is a chance that thiotepa may cause birth defects if it is taken at the time of conception or if it is taken during pregnancy. If your child is sexually active, it is best that they use some kind of birth control while receiving thiotepa. Tell the doctor right away if your child may be pregnant.</p> <p>After receiving thiotepa, your child may not be able to have children or have more difficulty having children. Your child's doctor will discuss this in more detail with you and your child.</p> <p>Check with your child's doctor or pharmacist before giving your child any other medicines (prescription, non-prescription, herbal, or natural products).</p><h2>What other important information should you know about thiotepa?</h2><ul><li>Keep a list of all medications your child is on and show the list to the doctor or pharmacist.<br></li></ul>
噻替哌噻替哌ThiotepaChineseSimplifiedPharmacyNANANADrugs and SupplementsAdult (19+) CaregiversNA2010-03-25T04:00:00ZRita V. Kutti, BScPhm, RPhFlat ContentDrug A-Z<p>你的孩子需要使用称为噻替哌的药物。此信息篇解释噻替哌做什么和如何给予,以及当你的孩子使用这种药物的时候,他或她可能有的副作用或问题。</p>





噻替哌252.000000000000噻替哌ThiotepaChineseSimplifiedPharmacyNANANADrugs and SupplementsAdult (19+) CaregiversNA2010-03-25T04:00:00ZRita V. Kutti, BScPhm, RPhFlat ContentDrug A-Z<p>你的孩子需要使用称为噻替哌的药物。此信息篇解释噻替哌做什么和如何给予,以及当你的孩子使用这种药物的时候,他或她可能有的副作用或问题。</p><h2>这是什么药?</h2><p>噻替哌是用于治疗各种类型癌症的药物。它也可以作为准备骨髓或干细胞移植的一部分给予。通常与其他药物共同使用。</p><p>噻替哌为注射剂型。</p><h2>在给予你的孩子这种药物之前</h2><p>如果你的孩子曾经对噻替哌或任何其他药品、食品、防腐剂,或着色剂有过严重反应,告诉你的医生。</p><h3>如果你的孩子有任何下列疾病,告知你的孩子的医生或药剂师。如果你的孩子有下列疾病,此药可能不适合他或她:</h3><ul><li> 感染或最近接触感染,(比如水痘)</li><li> 肾脏或肝脏问题</li></ul><h2>你的孩子将如何得到这种药物?</h2><p>噻替哌是一种透明液体,由护士注射入你的孩子的静脉(静脉注射或IV)。你的孩子通常在医院门诊或在护理室给予这种药物。</p><h2>这种药物的可能的副作用是什么?</h2><p>当你的孩子使用噻替哌时,他或她可能有一些副作用。如果你的孩子继续有任何下面副作用,而且它们没有消失,或者它们烦扰你的孩子,与你的孩子的医生协商:</p><ul><li> 头晕或嗜睡</li><li> 不感到饥饿或食欲不振</li><li> 恶心(胃部不适)或呕吐</li></ul><p>如果你的孩子有任何这些副作用,在办公时间致电你的孩子的医生:</p><ul><li> 关节疼痛</li><li> 在注射疼痛的地方</li><li> 脚或小腿肿胀</li><li> 口腔或嘴唇溃疡</li></ul><h3>大多数这些副作用是不常见的,但是,它们可能是一个严重问题的征兆。如果你的孩子有任何以下这些症状,立刻打电话给你的孩子的医生,或带你的孩子去急诊:</h3><ul><li> 发烧或发冷</li><li> 咳嗽或喉咙疼痛</li><li> 尿液或大便中有血<br></li><li> 黑色柏油样大便</li><li> 皮肤上有小的红色斑点</li><li> 排尿疼痛或排尿困难</li><li> 腰部或侧面疼痛</li><li> 喉咙紧</li><li> 气喘或呼吸困难</li><li> 荨麻疹(皮肤上有凸起、红痒部位)</li><li> 癫痫发作(抽搐)</li></ul><h2>当你的孩子使用这种药物时,你应该采取什么安全措施?</h2><p>在你的孩子做任何手术,即使是牙齿手术,或一个紧急治疗之前,告诉医生或牙医你的孩子正在使用噻替哌。</p><p>保持在门诊或医生办公室的所有预约,这样医生可以检查你的孩子对噻替哌的反应。</p><p>你的孩子将收到防止噻替哌造成的胃部不适和呕吐的药物。</p><p>噻替哌可能造成口腔溃疡。使用小苏打漱口水冲洗你的孩子的嘴,以帮助保持干净。你的护士或药剂师可以告诉你这一点。不要使用商店购买的含有酒精的漱口水,因为它可能刺痛,并导致口干。</p><p>当接受噻替哌时,你的孩子的皮肤可能变黑,特别是在肘部和膝盖和皮肤皱折部位。如果发生这种情况,一旦你的孩子停止服用噻替哌,它会慢慢消失。</p><p>噻替哌治疗后,这种药可能通过汗水(出汗)的一部分透过皮肤。这可以导致皮肤刺激,并可以导致皮肤变色。它也可能意味着你或你的孩子的照顾者有机会接触到少量的这种药物。因此,你的孩子的医生或护士可能会建议:</p><ul><li> 当你的孩子接受噻替哌时,经常洗澡:当你给你的孩子洗澡的时候,要特别注意皮肤的褶皱部位(例如腋窝、腹股沟,肘部和膝盖背面)。充分地清洗所有部位。并拍干。避免摩擦,这样可能会伤害皮肤。</li><li> 定期更换你的孩子的衣服或床单</li><li> 考虑手套和/或袍子,以保护你自己避免接触噻替哌</li></ul><p>你的孩子可能失去他们的头发。一旦你的孩子不再接受噻替哌,头发将重新生长。头发的颜色和质地可能有所变化。使用温和的洗发水和软的刷子。</p><p>噻替哌可能暂时降低血液中白血球的数量,增加了你的孩子受感染的机会。你的孩子可以采取以下措施,以预防感染,特别是当血液计数低的时候:</p><ul><li> 避免接触有感染的人,比如感冒或流感。</li><li> 避免到有大量人群非常拥挤的地方。</li><li> 当刷牙或使用牙线清洁你的孩子的牙齿时,要小心。你的医生、护士,或牙医可能会建议不同的方法来清洁你的孩子的口腔和牙齿。</li><li> 在接触你的孩子的眼睛或鼻子里之前,你或你的孩子的手应该干净。</li><li> 你的孩子的护士将与你讨论万一有发烧的情况下,你做什么。</li></ul><p>噻替哌可以降低血液中的血小板数量,从而增加你的孩子出血的风险。你可以采取以下预防措施:</p><ul><li> 当使用剃刀、指甲剪刀,或脚趾指甲刀剪的时候,小心不要刺伤你的孩子。</li><li> 你的孩子应该避免可能发生瘀伤或受伤的接触性运动。</li><li> 在你的孩子做手术之前,包括牙科手术,告诉医生或牙医你的孩子正在使用噻替哌。</li><li> 你的孩子不应该接受永久性纹身或任何类型的身体穿孔。</li></ul><p>没有你的孩子的医生的批准,你的孩子不应该接受任何预防接种(疫苗)。当你的孩子正在接受癌症治疗时,你的孩子或你的家庭中的任何其他人不应该接受口服脊髓灰质炎疫苗。如果你的家庭中的任何人最近接受了口服脊髓灰质炎疫苗,告诉你的孩子的医生。你的孩子应该避免接触任何最近接受了这种疫苗的人。</p><p>如果在受孕时,或者如果在怀孕期间使用噻替哌,有可能有导致出生缺陷的机会。如果你的孩子是性活跃的,当接受噻替哌的时候,他或她最好使用某种类型的节育措施。如果你的孩子可能怀孕,立即告诉你的医生。</p><p>在接受噻替哌之后,你的孩子可能无法生育,或有更多的困难生育。你的孩子的医生将与你和你的孩子详细讨论这一点。</p><p>在给予你的孩子任何其它药物(处方药、非处方药、草药或天然产品)之前,与你的孩子的医生或药剂师协商。</p><h2>你还应该知道其它什么重要信息?</h2><p>保留一个列有你的孩子正在使用的所有药物的清单,向医生或药剂师出示这个清单。</p><p>把药物保存在你的孩子看不见和接触不到的地方,并锁在一个安全的地方。如果你的孩子使用了过量的药物,拨打以下电话之一与安大略省中毒中心联系。这些电话都是免费的。</p><ul><li>如果你住在多伦多, 致电416-813-5900。</li><li>如果你住在安大略省的其它地区, 致电1-800-268-9017。 </li><li>如果你住在安大略省以外,致电当地的中毒信息中心。 </li></ul><p>免责声明:本家庭医学援助中的信息在付印时是准确的。它提供了有关噻替哌的信息摘要, 不包含有关此药的所有可能的信息。没有列出所有的副作用。如果你有任何疑问或想了解更多有关噻替哌的信息, 告诉你的医护人员。 </p><br>https://assets.aboutkidshealth.ca/AKHAssets/ICO_DrugA-Z.png噻替哌False

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