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Steroids for brain tumoursSSteroids for brain tumoursSteroids for brain tumoursEnglishNeurology;OncologyChild (0-12 years);Teen (13-18 years)BrainNervous systemDrug treatmentAdult (19+)NA2009-07-10T04:00:00ZEric Bouffet, MD, FRCPCUte Bartels, MD9.0000000000000056.0000000000000929.000000000000Flat ContentHealth A-Z<p>An in-depth discussion of steroid treatment for children with brain tumours. Answers provided by Canadian Paediatric Hospitals.</p><p>Your child may be given a type of medicine called a steroid. Steroids are given to manage some of the symptoms of the tumour. The steroid that is most commonly used with brain tumours is dexamethasone. It is sold as Decadron. </p> <p>Dexamethasone falls into the group of steroids known as glucocorticosteroids. These are different from anabolic steroids, which some athletes use illegally. They are also different from sex steroids (or sex hormones) such as estrogen and testosterone. Glucocorticosteroids are used to manage many medical conditions. </p><h2>Key points</h2> <ul><li>Steroids are given to manage symptoms of brain tumours by reducing swelling in normal tissues.</li> <li>It is very important that you child takes dexamethasone exactly as the treatment team has told you.</li> <li>Dexamethasone can cause unpleasant side effects such as digestive problems, sleep problems, water retention, skin problems, and weakness.</li></ul>
Stéroïdes des tumeurs cérébralesSStéroïdes des tumeurs cérébralesSteroids for low grade gliomasFrenchNeurology;OncologyChild (0-12 years);Teen (13-18 years)BrainNervous systemDrug treatmentAdult (19+)NA2009-07-10T04:00:00ZEric Bouffet, MD, FRCPC Ute Bartels, MD9.0000000000000056.0000000000000929.000000000000Flat ContentHealth A-Z<p>Discussion approfondie au sujet du traitement par les stéroïdes pour les enfants atteints de gliomes de bas grade. Réponses fournies par les hôpitaux pédiatriques canadiens.</p><p>On pourrait donner à votre enfant un type de médicament appelé stéroïde. Les stéroïdes sont administrés afin d’atténuer certains des symptômes de la tumeur. Le stéroïde le plus utilisé pour les tumeurs cérébrales et la dexaméthasone. Elle est vendue sous le nom de Decadron. </p> <p>La dexaméthasone fait partie du groupe de stéroïdes connus sous le nom de glucocorticoïdes. Ils sont différents des stéroïdes anabolisants, que certains athlètes utilisent illégalement. Ils sont aussi différents des stéroïdes sexuels (ou hormones sexuelles) comme l’œstrogène et la testostérone. Les glucocorticoïdes sont utilisés pour atténuer de nombreux troubles médicaux.</p><h2>À retenir</h2> <ul><li>Des stéroïdes sont administrés afin d'atténuer certains des symptômes des tumeurs cérébrales en réduisant l’enflure des tissus sains.</li> <li>Il est très important que votre enfant prenne de la dexaméthasone comme indiqué par l’équipe de traitement.</li> <li>La dexaméthasone peut occasionner certains effets indésirables tels que des troubles digestifs, des troubles du sommeil, de la rétention d’eau, des problèmes de peau et de la faiblesse.</li></ul>

 

 

Steroids for brain tumours1354.00000000000Steroids for brain tumoursSteroids for brain tumoursSEnglishNeurology;OncologyChild (0-12 years);Teen (13-18 years)BrainNervous systemDrug treatmentAdult (19+)NA2009-07-10T04:00:00ZEric Bouffet, MD, FRCPCUte Bartels, MD9.0000000000000056.0000000000000929.000000000000Flat ContentHealth A-Z<p>An in-depth discussion of steroid treatment for children with brain tumours. Answers provided by Canadian Paediatric Hospitals.</p><p>Your child may be given a type of medicine called a steroid. Steroids are given to manage some of the symptoms of the tumour. The steroid that is most commonly used with brain tumours is dexamethasone. It is sold as Decadron. </p> <p>Dexamethasone falls into the group of steroids known as glucocorticosteroids. These are different from anabolic steroids, which some athletes use illegally. They are also different from sex steroids (or sex hormones) such as estrogen and testosterone. Glucocorticosteroids are used to manage many medical conditions. </p><h2>Key points</h2> <ul><li>Steroids are given to manage symptoms of brain tumours by reducing swelling in normal tissues.</li> <li>It is very important that you child takes dexamethasone exactly as the treatment team has told you.</li> <li>Dexamethasone can cause unpleasant side effects such as digestive problems, sleep problems, water retention, skin problems, and weakness.</li></ul><h2>Why does my child need dexamethasone?</h2> <p>Brain tumours cause swelling (edema) in the normal tissues near the tumour, leading to symptoms. Dexamethasone reduces swelling in normal tissues. It is prescribed as needed, and may be taken one or more times a day in a tablet or as a liquid. </p> <p>Dexamethasone may be given:</p> <ul> <li> at the time of diagnosis, to ease symptoms such as headache, nausea, and vomiting </li> <li> with surgery, to reduce swelling after an operation </li> <li> with radiation therapy, to reduce the swelling that may occur during treatment </li> <li> for long-term use to reduce symptoms</li></ul> <p>Dexamethasone does not have an effect on the tumour. The benefit is only temporary.</p> <h2>Important information about dexamethasone</h2> <p>Your child needs to take dexamethasone exactly as the treatment team has told you. It can be dangerous for your child to stop taking it suddenly. This is because your child’s body stops making its own steroids when they are taking dexamethasone. Steroids are involved in many important functions in the body, such as helping the body respond to stress. If your child suddenly stops taking dexamethasone, they will have no steroids at all. </p> <p>Your child’s treatment team will talk to you about how you can gradually reduce the dose of dexamethasone when it is appropriate, or “wean” your child, so that it is safe. </p> <h2>What are the side effects of dexamethasone?</h2> <p>Even though they may make your child feel much better, dexamethasone may produce some unpleasant side effects. Most of these will end once treatment is over. However, in some cases dexamethasone may need to be used for months, and then certain effects will last longer. </p> <h3>Side effects</h3> <ul> <li> Stomach irritation: Dexamethasone can cause stomach irritation that feels like heartburn. Make sure your child takes dexamethasone with food. Your child may be given antacids, such as ranitidine (Zantac), that reduce acid production. </li> <li> Stomach problems: If your child has problems with bowel movements, they may be given a stool softener. It makes bowel movements easier. </li> <li> Personality changes, such as irritability: This is sometimes seen in children taking dexamethasone. It can be mild symptoms such as mood swings or crying easily, or more serious such as bizarre behaviour. This side effect will go away when the dexamethasone use is stopped, or the dose is reduced. </li> <li> Sleeping problems: Mild exercise before bed, such as a walk around the block, may help. If your child has several daily doses of dexamethasone, give the last dose no later than 6 pm. </li> <li> Increased appetite: Your child may develop a huge appetite when they are given high doses of dexamethasone. As a result, they may gain weight. Most of the extra weight is from fluids that the body retains while on dexamethasone. As a result of weight gain, your child may develop stretch marks, which are not reversible. </li> <li> Make sure your child is eating healthy, well-balanced meals while their appetite is good. Avoid foods with high amounts of salt, as they can add to the water retention. Keep lots of low calorie snacks on hand, such as fruits and vegetables, or popcorn without salt or butter. </li> <li> Your child’s appetite should return to normal and the weight will drop once they stop taking dexamethasone. If they continue to gain weight, talk to the treatment team. </li> <li> Increase in thirst and more peeing: This may indicate an increase in blood sugar levels. Talk to your child’s treatment team. In some cases, the dietitian may recommend a low concentrated carbohydrate diet for your child. </li> <li> Water retention: Your child may have swelling in their hands, feet, or around their face. Raise your child’s feet when they ar sitting. Avoid tight fitting clothing. Avoid adding extra salt to foods, or serving foods with lots of salt (sodium), such as processed foods. </li> <li> Skin problems: Some of the problems that may develop are acne or hair on the shoulders or back. The acne usually goes away when the dose of the dexamethasone is reduced. Stretch marks may occur due to rapid weight gain and they are not reversible. Talk to the treatment team about how to deal with these effects. </li> <li> Weakness: Your child may feel weak when walking up stairs or standing up from a sitting position. This side effect should go away when dexamethasone use stops. </li> <li> Increased risk of infection: Dexamethasone can lower your child’s resistance to infections such as measles or chicken pox. </li></ul> <h3>Side effects from long-term use</h3> <ul> <li> Bone loss (osteoporosis): There are certain measures you can take to prevent bone loss while your child is taking dexamethasone. Make sure your child stays physically active as much as positive. Each day, they need to have a good intake of calcium, an important mineral found in bones, and vitamin D to help the bones absorb calcium. Talk to your child’s treatment team for further information. </li> <li> High blood pressure: Avoid adding extra salt to food, or giving your child foods with lots of salt (sodium), such as processed foods. </li> <li> Muscle wasting: The muscles involved in standing, walking, and moving the arms (proximal muscles) may become weak. Make sure your child stays physically active as much as possible. Muscle weakness may be improved by reducing the dose of dexamethasone. Rehabilitation, such as physical or occupational therapy, may also help. </li></ul>Steroids for brain tumours

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