Late effects after an allogeneic transplantLLate effects after an allogeneic transplantLate effects after an allogeneic transplantEnglishHaematology;Immunology;OncologyChild (0-12 years);Teen (13-18 years)BodyImmune systemNATeen (13-18 years) Adult (19+)NA2010-03-19T04:00:00ZJohn Doyle, MD, FRCPC, FAAPChristine Armstrong, RN, MScN, NP Peds8.0000000000000062.0000000000000261.000000000000Flat ContentHealth A-Z<p>Learn about the potential late effects after your child's allogeneic transplant.</p><p>Some of the drugs and treatments used to prepare your child for an allogeneic blood and marrow transplant (BMT) may cause damage to healthy cells in the body. This can appear as side effects years later, after your child finishes treatment.</p><h2>Key points</h2> <ul><li>Chemotherapy medicines taken before a BMT may cause side effects for your child later in life, after treatment has ended.</li> <li>Some late effects may be due to the transplant itself.</li></ul>
Effets tardifs après une greffe allogéniqueEEffets tardifs après une greffe allogéniqueLate effects after an allogeneic transplantFrenchHaematology;Immunology;OncologyChild (0-12 years);Teen (13-18 years)BodyImmune systemNATeen (13-18 years) Adult (19+)NA2010-03-19T04:00:00ZJohn Doyle, MD, FRCPC, FAAPChristine Armstrong, RN, MScN, NP Peds8.0000000000000062.0000000000000261.000000000000Flat ContentHealth A-Z<p>Apprendrez davantage sur les effets tardifs potentiels après une greffe allogénique.</p><p>Certains médicaments et traitements utilisés pour préparer votre enfant à une greffe de sang et de moelle osseuse allogénique peuvent causer des dommages aux cellules saines du corps. Ces dommages pourraient se présenter sous forme d’effets secondaires des années après que votre enfant a reçu son traitement.</p><h2>À retenir</h2> <ul><li>La chimiothérapie reçue avant une greffe de sang et de moelle osseuse peut causer des effets secondaires à votre enfant plus tard dans la vie après la fin du traitement.</li> <li>Certains effets tardifs peuvent être dus à la greffe elle-même.</li></ul>

 

 

Late effects after an allogeneic transplant1568.00000000000Late effects after an allogeneic transplantLate effects after an allogeneic transplantLEnglishHaematology;Immunology;OncologyChild (0-12 years);Teen (13-18 years)BodyImmune systemNATeen (13-18 years) Adult (19+)NA2010-03-19T04:00:00ZJohn Doyle, MD, FRCPC, FAAPChristine Armstrong, RN, MScN, NP Peds8.0000000000000062.0000000000000261.000000000000Flat ContentHealth A-Z<p>Learn about the potential late effects after your child's allogeneic transplant.</p><p>Some of the drugs and treatments used to prepare your child for an allogeneic blood and marrow transplant (BMT) may cause damage to healthy cells in the body. This can appear as side effects years later, after your child finishes treatment.</p><h2>Key points</h2> <ul><li>Chemotherapy medicines taken before a BMT may cause side effects for your child later in life, after treatment has ended.</li> <li>Some late effects may be due to the transplant itself.</li></ul><p>During your child’s BMT, they take many chemotherapy medicines. The treatment is an effective way to prepare your child’s body for the transplant. </p> <p>These drugs are important because they:</p> <ul> <li>suppress your child’s immune system so that the new stem cells can be accepted into your child’s bone marrow space. This is called engraftment. When the transplanted cells engraft, your child’s marrow should start producing new, healthy blood cells.</li> <li>kill your child’s diseased marrow cells. Although this depends on your child’s diagnosis.</li></ul> <p>However, some of these medicines may also damage healthy cells in different parts of the body. This can appear as side effects many years after your child finishes treatment. These are called late effects.</p> <p>Many of the potential late effects are a consequence of certain kinds of chemotherapy. Some children also receive radiation to the entire body. This type of radiation therapy is called <a href="/Article?contentid=1528&language=English">total body irradiation</a> (TBI). It includes radiation to the brain, which may put your child more at risk for some of the effects discussed in this section. </p> <p>Because children with various illnesses are treated with BMT, your child may experience late effects that are due to their treatment before the transplant. However, there are some complications that may be more related to the transplant itself. </p> <p>Learning about the possible late effects may be overwhelming. Keep in mind that these are the potential late effects and not necessarily what your child will develop. Many BMT survivors go on to lead healthy and productive lives. Being aware of possible late effects will help you look for early signs and get the best treatment right away.</p>Late effects after an allogeneic transplant

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