Marfan Syndrome and Congenital Heart ConditionsMMarfan Syndrome and Congenital Heart ConditionsMarfan Syndrome and Congenital Heart ConditionsEnglishCardiologyChild (0-12 years);Teen (13-18 years)HeartCardiovascular systemConditions and diseasesAdult (19+)NA2009-12-14T05:00:00ZFraser Golding, MD, FRCPC10.000000000000046.0000000000000291.000000000000Flat ContentHealth A-Z<p>Marfan syndrome is a rare hereditary disorder of connective tissue. About 60% to 80% of people with this syndrome have heart problems.</p><p> Children with Marfan syndrome, a rare disorder of connective tissue, often have heart conditions.</p><h2> Key points </h2> <ul><li>Marfan syndrome is a rare disorder caused by a mutation to a gene on chromosome 15 that results in weak connective tissues.</li> <li> Children with Marfan syndrome develop physical problems but can lead healthy, normal lives. </li> <li> Children with Marfan syndrome often experience heart problems and will need to be monitored regularly.</li></ul>
Syndrome de Marfan et les anomalies cardiaques congénitalesSSyndrome de Marfan et les anomalies cardiaques congénitalesMarfan Syndrome and Congenital Heart ConditionsFrenchCardiologyChild (0-12 years);Teen (13-18 years)HeartCardiovascular systemConditions and diseasesAdult (19+)NA2009-12-14T05:00:00ZFraser Golding, MD, FRCPC10.000000000000046.0000000000000291.000000000000Flat ContentHealth A-Z<p>Le syndrome de Marfen est une maladie héréditaire rare des tissus conjonctifs. Environ 60 à 80 % des personnes atteintes de ce syndrome souffrent d’une cardiopathie.</p><p> Les enfants atteints du syndrome de Marfan, une maladie grave des tissus conjonctifs, souffrent souvent d’une cardiopathie. </p><h2> À retenir </h2> <ul><li> Ce syndrome est une maladie rare causée par la mutation d’un gène situé sur le chromosome 15 qui entraîne une faiblesse des tissus conjonctifs.</li> <li> Les enfants atteints du syndrome de Marfan ont des problèmes physiques, mais ils peuvent avoir une vie normale et rester en bonne santé. </li> <li>Ils souffrent souvent de problèmes cardiaques et devront régulièrement se soumettre à des contrôles.</li></ul>

 

 

Marfan Syndrome and Congenital Heart Conditions1636.00000000000Marfan Syndrome and Congenital Heart ConditionsMarfan Syndrome and Congenital Heart ConditionsMEnglishCardiologyChild (0-12 years);Teen (13-18 years)HeartCardiovascular systemConditions and diseasesAdult (19+)NA2009-12-14T05:00:00ZFraser Golding, MD, FRCPC10.000000000000046.0000000000000291.000000000000Flat ContentHealth A-Z<p>Marfan syndrome is a rare hereditary disorder of connective tissue. About 60% to 80% of people with this syndrome have heart problems.</p><p> Children with Marfan syndrome, a rare disorder of connective tissue, often have heart conditions.</p><h2> Key points </h2> <ul><li>Marfan syndrome is a rare disorder caused by a mutation to a gene on chromosome 15 that results in weak connective tissues.</li> <li> Children with Marfan syndrome develop physical problems but can lead healthy, normal lives. </li> <li> Children with Marfan syndrome often experience heart problems and will need to be monitored regularly.</li></ul><h2>What is Marfan syndrome?</h2> <p>Marfan syndrome is a rare hereditary disorder of connective tissue that results in an individual being very tall and having long arms and legs. About 1 in 5,000 babies are born with this disorder. These children often have curvature of the spine, an unusually shaped breastbone, and excessive flexibility, and may develop vision problems. These features result from having weak connective tissues in the body. </p> <h2>What causes Marfan syndrome?</h2> <p>Marfan syndrome is caused by a mutation to a gene on chromosome 15. This gene controls the making of the protein fibrillin, which provides structural support for many tissues in the body. </p> <h2>What heart conditions may be associated with Marfan syndrome?</h2> <p>The syndrome affects a number of parts of the body, particularly the heart, in about 60% to 80% of children with Marfan syndrome. Heart conditions may include mitral valve prolapse and enlargement of the aorta. An echocardiogram is necessary to make a diagnosis of Marfan syndrome. </p> <p>Regular echocardiograms are often needed to monitor the size and function of the heart and aorta. Later in life, many people with Marfan syndrome develop so much enlargement of the aorta that they may need open heart surgery to replace the aortic root. Before then, drugs called beta blockers are used to slow down the heart rate and reduce damage to the aorta. </p> <h2>What is the long-term outlook for children with Marfan syndrome?</h2> <p>With monitoring and treatment, the lifespan is normal and the outlook positive for people with Marfan syndrome. Their main challenges are the physical problems described above. Children with Marfan syndrome generally lead full, normal lives, with the adequate monitoring and management of symptoms. </p> <p>For more information about Marfan syndrome, please ask to be referred to a genetic counsellor.</p>Marfan Syndrome and Congenital Heart Conditions

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