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Infection and the immune system of a premature babyIInfection and the immune system of a premature babyInfection and the immune system of a premature babyEnglishNeonatology;ImmunologyPremature;Newborn (0-28 days);Baby (1-12 months)BodyImmune systemNAPrenatal Adult (19+)NA2009-10-31T04:00:00ZAndrew James, BSc, MBChB, FRACP, FRCPCAideen Moore, MD, FRCPC, MRCPI, MHSc12.000000000000032.0000000000000433.000000000000Flat ContentHealth A-Z<p>Read about infections and the immune system of premature babies. A premature baby is susceptible to infection because their immune system is immature.</p><p>Premature babies are typically more vulnerable to infections because their immune systems are immature. The lack of antibodies and immunity in a premature baby's immune system means they can't fight off bacteria, viruses or fungi in the same way that full-term babies may be able to.</p><h2>Key points</h2> <ul><li>Over time, the immune system is exposed to different bacteria, viruses, and fungi, and develop antibodies to respond to these invading organisms and develop immunities to their effects.</li> <li>Usually, a mother's antibodies cross through the placenta during the third trimester of pregnancy, which gives a newborn some immunity to diseases it has not yet been exposed to.</li> <li>Premature babies may not have received enough antibodies from the mother, and may also have difficulty producing white blood cells and antibodies to fight off infection.</li> <li>Infection in a premature baby can come from many sources including the womb, the birth canal, or the Neonatal Intensive Care Unit (NICU) environment.</li></ul>
Les infections et le système immunitaire d'un bébé prématuréLLes infections et le système immunitaire d'un bébé prématuréInfection and the immune system of a premature babyFrenchNeonatology;ImmunologyPremature;Newborn (0-28 days);Baby (1-12 months)BodyImmune systemNAPrenatal Adult (19+)NA2009-10-31T04:00:00ZAndrew James, BSc, MBChB, FRACP, FRCPCAideen Moore, MD, FRCPC, MRCPI, MHSc12.000000000000032.0000000000000433.000000000000Flat ContentHealth A-Z<p>Lisez au sujet des infections et du système immunitaire des bébés prématurés. Un bébé prématuré est susceptible de contracter une infection à cause de son système immunitaire immature.</p><p>Les bébés prématurés sont typiquement plus vulnérables aux infections en raison de l’immaturité de leur système immunitaire. Le manque d’anticorps et d’immunité du système immunitaire d’un bébé prématuré signifie qu’il ne peut pas combattre les bactéries, les virus ou les champignons de la même façon que les bébés nés à terme.</p><h2>À retenir</h2> <ul><li>Avec le temps, le système immunitaire est exposé à différentes bactéries, différents virus et différents champignons et il développe des anticorps afin de répondre à ces organismes étrangers et de développer une immunité contre eux.</li> <li>Habituellement, les anticorps de la mère traversent le placenta au cours du troisième trimestre de grossesse, donnant au nouveau-né une immunité à des maladies auxquelles il n’a pas encore été exposé.</li> <li>Les bébés prématurés peuvent ne pas avoir reçu suffisamment d’anticorps maternels et peuvent aussi éprouver de la difficulté à produire des globules blancs et des anticorps afin de combattre les infections.</li> <li>L’infection peut provenir de différentes sources chez un bébé prématuré, dont l’utérus, le canal génital ou l’environnement de l’unité des soins intensifs néonatals.</li></ul>

 

 

Infection and the immune system of a premature baby1778.00000000000Infection and the immune system of a premature babyInfection and the immune system of a premature babyIEnglishNeonatology;ImmunologyPremature;Newborn (0-28 days);Baby (1-12 months)BodyImmune systemNAPrenatal Adult (19+)NA2009-10-31T04:00:00ZAndrew James, BSc, MBChB, FRACP, FRCPCAideen Moore, MD, FRCPC, MRCPI, MHSc12.000000000000032.0000000000000433.000000000000Flat ContentHealth A-Z<p>Read about infections and the immune system of premature babies. A premature baby is susceptible to infection because their immune system is immature.</p><p>Premature babies are typically more vulnerable to infections because their immune systems are immature. The lack of antibodies and immunity in a premature baby's immune system means they can't fight off bacteria, viruses or fungi in the same way that full-term babies may be able to.</p><h2>Key points</h2> <ul><li>Over time, the immune system is exposed to different bacteria, viruses, and fungi, and develop antibodies to respond to these invading organisms and develop immunities to their effects.</li> <li>Usually, a mother's antibodies cross through the placenta during the third trimester of pregnancy, which gives a newborn some immunity to diseases it has not yet been exposed to.</li> <li>Premature babies may not have received enough antibodies from the mother, and may also have difficulty producing white blood cells and antibodies to fight off infection.</li> <li>Infection in a premature baby can come from many sources including the womb, the birth canal, or the Neonatal Intensive Care Unit (NICU) environment.</li></ul><h2>The immune system</h2><p>The immune system is made up of special cells, proteins, tissues, and organs that defend against infections caused by foreign micro-organisms such as bacteria, viruses, or fungi that do not belong in the body. Over time, the immune system is exposed to different bacteria, viruses, and fungi, and develop antibodies to respond to these invading organisms and develop immunities to their effects. For example, children often are exposed to the virus that causes chicken pox. After the first infection, the child’s immune system will develop antibodies and therefore immunity, and if exposed to the same virus again, the child will not get chicken pox again. At birth, the premature baby will not have a well developed immune system and exposure to new organisms will place the baby at risk for infection.</p><p>Usually, a mother's antibodies cross through the placenta during the third trimester of pregnancy. This give the newborn some immunity to diseases that it has not yet been exposed to in the outside environment. Because premature babies miss either some or even all of the third trimester, much less of the mother's immunity is transfered to the baby before birth. This makes premature babies more vulnerable to infection once outside the womb.</p><p>Additionally, the premature baby’s immune system may have difficulty producing the necessary cells and proteins that make up the components of the system. For example, white blood cells and antibodies are an integral part of the immune system, and a premature baby may be inefficient at producing these cells and proteins.</p><h2>Infection</h2><p>Infection takes place when foreign organisms, such as bacteria, viruses, or fungi, invade the body, or an organism that occurs normally on the body becomes infectious because of decreased immunity of the baby. Infection in a premature baby can come from many sources including the womb, the birth canal, or the Neonatal Intensive Care Unit (NICU) environment. Infection may affect some or all parts of the body, and can have varying degrees of severity. In general, the body responds to infection with inflammation and attempts to destroy the foreign organisms with white blood cells (WBCs) and antibodies. The premature baby may not be able to produce enough WBCs and/or antibodies on their own to fight the infection. In addition, although the premature baby may have received some antibodies from their mother in the womb, since antibodies pass across the placenta, these may not be sufficient to fully fight the infection. The premature baby may become very unwell because of an infection. There may be lethargy, diminished responsiveness, fever, abnormalities with temperature control, abnormal breathing, and reduced circulation of the blood to the body.</p><p>In general, infections are treated with antibiotics. While they are very often effective, antibiotics have side effects. In addition to killing the organisms that are causing the infection, antibiotics will also kill so-called “good” bacteria in the baby’s body. This effect may allow more resistant organisms to colonize the baby’s body and cause new and more serious types of infection.</p><h4>More information</h4><ul><li> <a href="/Article?contentid=1814&language=English">Diagnosis of infection </a></li><li> <a href="/Article?contentid=1847&language=English">Treatment of infection</a></li></ul>https://assets.aboutkidshealth.ca/akhassets/mom_looking_in_isolette_BRA_EN.jpgInfection and the immune system of a premature baby

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