AdalimumabAAdalimumabAdalimumabEnglishPharmacyNANAImmune systemDrugs and SupplementsCaregivers Adult (19+)NA2013-01-23T05:00:00ZElaine Lau, BScPhm, PharmD, MSc, RPh000Drugs (A-Z)Drug A-Z<p>This Family Med-aid provides detailed information on adalimumab, what it does, how to give it, and what side effects or problems your child may have when they take this medicine.</p><p>Your child needs to take the medicine called adalimumab. This information sheet explains what adalimumab does, how to give it, and what side effects or problems your child may have when they take this medicine.<br></p><h2>Before giving adalimumab to your child </h2><p>Tell your child's doctor if your child: </p><ul><li>has an allergy to adalimumab or any of the ingredients in the adalimumab injection.</li><li>is scheduled to receive any vaccinations. </li></ul><p>Talk with your child's doctor or pharmacist if your child has any of the following conditions. Precautions may need to be taken with this medicine if your child has: </p><ul><li>a latex allergy.</li><li>an infection (bacterial, fungal, or viral), especially serious infections such as tuberculosis (TB) or hepatitis B.</li><li>congestive heart failure (heart cannot pump enough blood to meet the body's needs).</li><li>demyelinating diseases of the nervous system (for example, multiple sclerosis).</li></ul><h2>How should you give your child adalimumab? </h2><p>Your child's first dose of adalimumab will likely be given in the hospital or in clinic. If your child is to receive adalimumab at home, arrangements may be made to have a nurse come into the home to give it. Alternatively, you may be taught by one of the nurses to give your child the subcutaneous (sc) injections (injections under the skin) at home. If you give the injections at home: </p><ul><li>Make sure you understand and are comfortable with the way to prepare and inject adalimumab and know how to dispose of the needle and syringe in a needle/sharps disposal container</li><li>Do not inject adalimumab at the same site. The injection site should be rotated</li> <li>Adalimumab should not be injected at sites that are red, tender, bruised, or hard. </li></ul><h2>What should you do if your child misses a dose of adalimumab? </h2><ul><li>Give the missed dose as soon as you re​​member.</li><li>If it is almost time for the next dose, skip the missed dose. Give the next dose at the regular time.</li><li>Do not give your child two doses to make up for one missed dose. </li></ul><h2>How long does adalimumabtake to work? </h2><p>Some patients see improvements after the​ir first or second dose of adalimumab, however it may take up to 3 months before the full benefit is seen. It is important to stay on track with the dosing schedule even if you see the effects right away. </p><h2>What are the possible side effects of adalimumab? </h2><p>Your child may have some of these side effects while they take adalimumab. Check with your child's doctor if your child continues to have any of these side effects, if they do not go away, or if they bother your child: </p><ul><li>Irritation, pain, or redness at the place of injection</li><li>Headache</li></ul><p>Most of the following side effects are not common, but they may be a sign of a serious problem. <strong>Call your child's doctor right away or take your child to Emergency</strong> if your child has any of these side effects: </p><ul><li>Signs of a life-threatening reaction, including: wheezing, shortness of breath, chest tightness or chest pain, difficulty breathing, fever, itching, bad cough, blue skin colour, swelling of the face, lips, tongue, or throat</li><li>Rash or hives (red raised spots on the skin), peeling or blisters on the skin</li><li>Signs of an infection, including: fever, chills, generally not feeling well (weak or tired), sore throat, runny nose, cough, and headache</li><li>Numbness or tingling</li><li>Sudden weight gain</li><li>Bruising or bleeding very easily, looking very pale </li></ul>​<h2>What safety measures should you take when your child is using adalimumab? </h2><p>There are some medicines that should not be taken together with adalimumab or in some cases the dose of adalimumab or the other medicine may need to be adjusted. It is important that you tell your doctor and pharmacist if your child takes any other medications (prescription, over the counter or herbal) including: </p><ul><li>abatacept (Orencia​)</li><li>anakinra (Kineret)</li><li>Immunosuppressants (for example, <a href="/Article?contentid=244&language=English">tacrolimus</a>, <a href="/Article?contentid=115&language=English">cyclosporine</a>, <a href="/Article?contentid=195&language=English">mycophenolate</a>, and <a href="/Article?contentid=221&language=English">prednisone</a>)</li><li>Live vaccines (for example, the measles, mumps, and rubella (MMR) vaccine, the chicken pox vaccine, and the oral polio vaccine)</li></ul><p>There have been rare cases of cancers in children and teenage patients taking TNF-blocking agents (such as adalimumab). For children taking TNF-blocker medicines, the chances of developing lymphoma or other cancers may increase. Although this risk is higher than the general population, it is still quite low. </p><p>It is important that your child be tested for tuberculosis (TB) and hepatitis B to make sure they do not have one of these infections before they receive adalimumab. </p><p>It is also important to make sure that your child's immunizations are up to date before they start therapy with adalimumab. Vaccines may not work as well if they are given to your child while they are being treated with adalimumab, or the vaccine dose may need to be adjusted. </p><h2>What other important information should you know about adalimumab? </h2><ul><li>Keep a list of all medications your child is on and show the list to the doctor or pharmacist. </li><li>Do not share your child's medicine with others and do not give anyone else's medicine to your child. </li><li>Make sure you always have enough adalimumab to last through weekends, holidays, and vacations. Call your pharmacy at least 2 days before your child runs out of medicine to order refills. </li><li>Keep adalimumab in the refrigerator. Do not freeze this medicine. Protect this medicine from light. </li><li>An adalimumab syringe can be stored at room temperature for a maximum of 14 days. Once taken out of the refrigerator for room temperature storage, the adalimumab syringe must be used within 14 days even if it is put back in the refrigerator. </li><li>Do not keep any medicines that are out of date. Check with your pharmacist about the best way to throw away outdated or leftover medicines.<br></li></ul>
AdalimumabAAdalimumabAdalimumabFrenchPharmacyNANAImmune systemDrugs and SupplementsCaregivers Adult (19+)NA2013-01-23T05:00:00Z​​Elaine Lau, BScPhm, PharmD, MSc, RPh​000Drugs (A-Z)Drug A-Z<p>La présente aide médicale à l'intention des familles vous renseigne de manière détaillée sur l'adalimumab.</p><p>Votre enfant doit prendre le médicament appelé adalimumab. La présente fiche d'information explique les effets désirables et indésirables de ce médicament, la façon de l'administrer, et les problèmes que votre enfant pourrait présenter lorsqu'il prend ce médicament.</p><h2>Avant d'administrer de l'adalimumab à votre enfant</h2> <p>Informez son médecin si votre enfant:</p> <ul><li>souffre d'une allergie à l'adalimumab ou à l'un des ingrédients présents dans l'injection d'adalimumab.</li> <li>doit se faire vacciner.</li></ul> <p>Informez son médecin ou le pharmacien si votre enfant souffre de l'une des pathologies suivantes. Il peut être nécessaire de prendre des précautions lors de l'administration du médicament si votre enfant a:</p> <ul><li>une allergie au latex.</li> <li>une infection (bactérienne, fongique ou virale), en particulier une infection grave comme la tuberculose (TB) ou l'hépatite B.</li> <li>une insuffisance cardiaque congestive (le cœur ne parvient pas à pomper suffisamment de sang pour répondre aux besoins de l'organisme).</li> <li>une maladie démyélinisante du système nerveux (par exemple, la sclérose en plaques).</li></ul><h2>Comment administrer l'adalimumab à votre enfant?</h2> <p>La première dose d'adalimumab sera probablement administrée à votre enfant à l'hôpital ou à la clinique. Si votre enfant doit se faire administrer le médicament à la maison, des dispositions peuvent être prises pour qu'une infirmière se présente à votre domicile pour procéder à l'injection. Alternativement, une infirmière pourrait vous apprendre à faire vous-même les injections sous-cutanées (sous la peau) à votre enfant à la maison. Si vous administrer les injections à domicile:</p> <ul><li>Assurez-vous d'avoir bien compris et d'être à l'aise avec la façon de préparer et d'injecter l'adalimumab et de savoir comment vous débarrasser de l'aiguille et de la seringue dans un récipient d'élimination des aiguilles et autres objets tranchants.</li> <li>Ne faites pas l'injection d'adalimumab au même endroit. Alternez les sites de piqûres.</li> <li>L'adalimumab ne doit pas être injecté là où la peau est rouge, tendre, meurtrie ou dure.</li></ul><h2>Que faire si votre enfant ne reçoit pas une dose programmée d'adalimumab?</h2> <ul><li>Administrez-lui la dose oubliée dès que possible.</li> <li>S'il est presque temps pour la prochaine dose, ne lui donnez pas la dose oubliée. Donnez la dose suivante à l'heure habituelle.</li> <li>N'administrez pas deux doses à la fois à votre enfant pour compenser une dose oubliée.</li></ul><h2>Combien de temps faut-il pour que l'adalimumab agisse?</h2> <p>Certains patients constatent des améliorations après leur première ou deuxième dose d'adalimumab, mais jusqu'à 3 mois peuvent s'écouler avant que ses bienfaits ne soient pleinement perçus. Il est important de respecter le programme de dosage même si le médicament tarde à avoir de l'effet.</p><h2>Quels sont les effets secondaires possibles de l'adalimumab?</h2> <p>Votre enfant pourrait présenter certains des effets secondaires associés au médicament pendant la période où il le prend. Consultez le médecin de votre enfant si ces effets secondaires persistent, s'ils ne disparaissent pas, ou s'ils incommodent votre enfant:</p> <ul><li>Irritation, douleur ou rougeur au point d'injection</li> <li>Mal de tête</li></ul> <p>La plupart des effets secondaires suivants ne sont pas courants, mais ils peuvent être le signe d'un problème sérieux. Appelez le médecin de votre enfant ou emmenez votre enfant au service d'urgence s'il présente l'un des effets secondaires suivants:</p> <ul><li>Il présente les signes d'une réaction potentiellement mortelle, notamment: la respiration sifflante, l'essoufflement, l'oppression thoracique ou la douleur thoracique, la difficulté à respirer, de la fièvre, des démangeaisons, une mauvaise toux, la peau bleue, le gonflement du visage, des lèvres, de la langue ou de la gorge</li> <li>Une éruption cutanée ou de l'urticaire (taches rouges en relief sur la peau), une desquamation de la peau ou des cloques</li> <li>Les signes d'une infection, notamment: la fièvre, les frissons, un état de malaise généralisé (fatigue ou faiblesse), des maux de gorge, l'écoulement nasal, la toux et des maux de tête</li> <li>L'engourdissement ou des fourmillements</li> <li>Un gain de poids soudain</li> <li>Des ecchymoses ou des saignements très fréquents, le teint pâle</li></ul><h2>Quelles mesures de sécurité adopter lorsque votre enfant prend de l'adalimumab?</h2> <p>Certains médicaments ne devraient pas être pris en même temps que l'adalimumab; dans certains cas, la dose d'adalimumab ou de l'autre médicament pourrait devoir être ajustée. Il est important que vous informiez son médecin et le pharmacien si votre enfant prend d'autres médicaments (sur ordonnance, en vente libre ou à base de plantes), y compris:</p> <ul><li>l'abatacept (OrenciaMD)</li> <li>l'anakinra (KineretMD)</li> <li>des immunodépresseurs (par exemple, le <a href="/Article?contentid=244&language=French">tacrolimus</a>, la <a href="/Article?contentid=115&language=French">cyclosporine</a>, le <a href="/Article?contentid=195&language=French">mycophénolate</a> et la <a href="/Article?contentid=221&language=French">prednisone​</a>)</li> <li>des vaccins vivants (par exemple, le vaccin contre la rougeole, les oreillons et la rubéole [ROR], le vaccin contre la varicelle et le vaccin antipoliomyélitique oral)</li></ul> <p>De rares cas de cancers ont été constatés chez les enfants et les adolescents prenant des inhibiteurs du FNT (comme l'adalimumab). Pour les enfants qui prennent des médicaments inhibiteurs du FNT, les risques de développer un lymphome ou d'autres cancers peuvent augmenter. Bien que ce risque soit plus élevé que chez la population générale, il reste assez faible.</p> <p>Avant que l'adalimumab ne lui soit administré, il est important que votre enfant subisse des analyses de dépistage de la tuberculose (TB) et de l'hépatite B afin de s'assurer qu'il n'est pas porteur de l'une de ces infections.</p> <p>Il est également important de veiller à ce que la vaccination de votre enfant soit à jour avant qu'il ne commence son traitement à l'adalimumab. Les vaccins pourraient ne pas être efficaces s'ils sont administrés à votre enfant pendant qu'il suit un traitement à l'adalimumab, ou la dose de vaccin pourrait devoir être ajustée.</p><h2>Quels autres renseignements importants devriez-vous savoir à propos de l'adalimumab?</h2><ul><li>Gardez une liste de tous les médicaments que prend votre enfant et montrez-la à son médecin ou au pharmacien.</li><li>Ne partagez pas les médicaments de votre enfant avec d'autres personnes et n'administrez à votre enfant que les médicaments qui lui ont été prescrits.</li><li>Assurez-vous de toujours avoir assez d'adalimumab pour les fins de semaine, les jours fériés et les vacances. Appelez votre pharmacien au moins 2 jours avant d'être à court de médicaments pour renouveler votre ordonnance.</li><li>Conservez l'adalimumab dans votre réfrigérateur. Ne congelez pas ce médicament. Protégez-le de la lumière.</li><li>Une seringue contenant de l'adalimumab peut être conservée à température ambiante pendant un maximum de 14 jours. Une fois sortie du réfrigérateur et à température ambiante, la seringue d'adalimumab doit être utilisée dans les 14 jours, même si vous la remettez au réfrigérateur.</li><li>Ne conservez pas les médicaments périmés. Consultez votre pharmacien pour connaître la meilleure façon de jeter les médicaments périmés ou inutilisés.<br></li></ul>

 

 

Adalimumab66.0000000000000AdalimumabAdalimumabAEnglishPharmacyNANAImmune systemDrugs and SupplementsCaregivers Adult (19+)NA2013-01-23T05:00:00ZElaine Lau, BScPhm, PharmD, MSc, RPh000Drugs (A-Z)Drug A-Z<p>This Family Med-aid provides detailed information on adalimumab, what it does, how to give it, and what side effects or problems your child may have when they take this medicine.</p><p>Your child needs to take the medicine called adalimumab. This information sheet explains what adalimumab does, how to give it, and what side effects or problems your child may have when they take this medicine.<br></p><h2>What is adalimumab? </h2><p>Adalimumab is a medicine that is​ used to treat diseases of the immune system including Juvenile Idiopathic Arthritis (JIA), uveitis, and Crohn's disease when other medicines have not worked. It works by lowering the body's harmful response from diseases of the immune system. Adalimumab is a type of medicine called a TNF-blocking agent and it belongs to a group of drugs known as monoclonal antibodies. You may hear adalimumab called by its brand name, Humira. Adalimumab comes as a liquid for injection in a pre-filled syringe. </p><h2>Before giving adalimumab to your child </h2><p>Tell your child's doctor if your child: </p><ul><li>has an allergy to adalimumab or any of the ingredients in the adalimumab injection.</li><li>is scheduled to receive any vaccinations. </li></ul><p>Talk with your child's doctor or pharmacist if your child has any of the following conditions. Precautions may need to be taken with this medicine if your child has: </p><ul><li>a latex allergy.</li><li>an infection (bacterial, fungal, or viral), especially serious infections such as tuberculosis (TB) or hepatitis B.</li><li>congestive heart failure (heart cannot pump enough blood to meet the body's needs).</li><li>demyelinating diseases of the nervous system (for example, multiple sclerosis).</li></ul><h2>How should you give your child adalimumab? </h2><p>Your child's first dose of adalimumab will likely be given in the hospital or in clinic. If your child is to receive adalimumab at home, arrangements may be made to have a nurse come into the home to give it. Alternatively, you may be taught by one of the nurses to give your child the subcutaneous (sc) injections (injections under the skin) at home. If you give the injections at home: </p><ul><li>Make sure you understand and are comfortable with the way to prepare and inject adalimumab and know how to dispose of the needle and syringe in a needle/sharps disposal container</li><li>Do not inject adalimumab at the same site. The injection site should be rotated</li> <li>Adalimumab should not be injected at sites that are red, tender, bruised, or hard. </li></ul><h2>What should you do if your child misses a dose of adalimumab? </h2><ul><li>Give the missed dose as soon as you re​​member.</li><li>If it is almost time for the next dose, skip the missed dose. Give the next dose at the regular time.</li><li>Do not give your child two doses to make up for one missed dose. </li></ul><h2>How long does adalimumabtake to work? </h2><p>Some patients see improvements after the​ir first or second dose of adalimumab, however it may take up to 3 months before the full benefit is seen. It is important to stay on track with the dosing schedule even if you see the effects right away. </p><h2>What are the possible side effects of adalimumab? </h2><p>Your child may have some of these side effects while they take adalimumab. Check with your child's doctor if your child continues to have any of these side effects, if they do not go away, or if they bother your child: </p><ul><li>Irritation, pain, or redness at the place of injection</li><li>Headache</li></ul><p>Most of the following side effects are not common, but they may be a sign of a serious problem. <strong>Call your child's doctor right away or take your child to Emergency</strong> if your child has any of these side effects: </p><ul><li>Signs of a life-threatening reaction, including: wheezing, shortness of breath, chest tightness or chest pain, difficulty breathing, fever, itching, bad cough, blue skin colour, swelling of the face, lips, tongue, or throat</li><li>Rash or hives (red raised spots on the skin), peeling or blisters on the skin</li><li>Signs of an infection, including: fever, chills, generally not feeling well (weak or tired), sore throat, runny nose, cough, and headache</li><li>Numbness or tingling</li><li>Sudden weight gain</li><li>Bruising or bleeding very easily, looking very pale </li></ul>​<h2>What safety measures should you take when your child is using adalimumab? </h2><p>There are some medicines that should not be taken together with adalimumab or in some cases the dose of adalimumab or the other medicine may need to be adjusted. It is important that you tell your doctor and pharmacist if your child takes any other medications (prescription, over the counter or herbal) including: </p><ul><li>abatacept (Orencia​)</li><li>anakinra (Kineret)</li><li>Immunosuppressants (for example, <a href="/Article?contentid=244&language=English">tacrolimus</a>, <a href="/Article?contentid=115&language=English">cyclosporine</a>, <a href="/Article?contentid=195&language=English">mycophenolate</a>, and <a href="/Article?contentid=221&language=English">prednisone</a>)</li><li>Live vaccines (for example, the measles, mumps, and rubella (MMR) vaccine, the chicken pox vaccine, and the oral polio vaccine)</li></ul><p>There have been rare cases of cancers in children and teenage patients taking TNF-blocking agents (such as adalimumab). For children taking TNF-blocker medicines, the chances of developing lymphoma or other cancers may increase. Although this risk is higher than the general population, it is still quite low. </p><p>It is important that your child be tested for tuberculosis (TB) and hepatitis B to make sure they do not have one of these infections before they receive adalimumab. </p><p>It is also important to make sure that your child's immunizations are up to date before they start therapy with adalimumab. Vaccines may not work as well if they are given to your child while they are being treated with adalimumab, or the vaccine dose may need to be adjusted. </p><h2>What other important information should you know about adalimumab? </h2><ul><li>Keep a list of all medications your child is on and show the list to the doctor or pharmacist. </li><li>Do not share your child's medicine with others and do not give anyone else's medicine to your child. </li><li>Make sure you always have enough adalimumab to last through weekends, holidays, and vacations. Call your pharmacy at least 2 days before your child runs out of medicine to order refills. </li><li>Keep adalimumab in the refrigerator. Do not freeze this medicine. Protect this medicine from light. </li><li>An adalimumab syringe can be stored at room temperature for a maximum of 14 days. Once taken out of the refrigerator for room temperature storage, the adalimumab syringe must be used within 14 days even if it is put back in the refrigerator. </li><li>Do not keep any medicines that are out of date. Check with your pharmacist about the best way to throw away outdated or leftover medicines.<br></li></ul>https://assets.aboutkidshealth.ca/AKHAssets/ICO_DrugA-Z.pngAdalimumabAdalimumab

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