Factor V Leiden mutation

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Thrombophilia is a blood clotting disorder that increases the risk of developing blood clots in the blood vessels. One of the most common causes of inherited thrombophilia is factor V Leiden. Learn about the symptoms, causes and management of FVL.

Key points

  • Factor V Leiden (FVL) increases the chance of developing a blood clot such as a deep vein thrombosis (DVT) or a pulmonary embolism (PE). DVT occurs in the deep veins of the arms or legs, while a PE is a clot that travels to the lungs.
  • Diagnosis of FVL occurs through a simple blood test.
  • Although there is no direct treatment for the FVL mutation, preventative measures like exercise, a healthy diet, and avoiding smoking and/or alcohol consumption, are some ways that the risk for developing blood clots can be reduced.
Last updated: April 16th 2021