Periodic fever adenitis pharyngitis aphthous ulcer (PFAPA) syndrome

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Information about the symptoms, causes, diagnosis and treatment of periodic fever adenitis pharyngitis aphthous ulcer (PFAPA) syndrome.

Key points

  • PFAPA is a disease that causes regular attacks of fever.
  • The attacks are usually accompanied by swollen neck glands, sore throat and/or sores in the mouth.
  • PFAPA can be treated with medications or removal of the tonsils.
  • PFAPA will go away in almost all children by the early teen years.
Last updated: June 5th 2019