Prothrombin gene mutation

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Thrombophilia is a blood clotting that increases the risk of developing blood clots in the blood vessels. The second most common type of inherited thrombophilia is the prothrombin gene mutation.

Key points

  • Prothrombin gene mutation increases the chance of developing a blood clot such as a deep venous thrombosis (DVT) or a pulmonary embolism (PE). DVT occurs in the deep veins of the arms or legs, while PE is a clot that travels to the lungs.
  • Diagnosis of the prothrombin gene mutation occurs through a blood test.
  • Although there is no direct treatment for prothrombin gene mutation, preventative measures like regular exercise, a healthy diet and avoiding smoking and/or alcohol consumption, are some ways that the risk for developing blood clots can be reduced.
Last updated: April 16th 2021