Cow's milk protein allergy (CMPA)

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Learn about the different types of allergic reactions that infants and children may experience to proteins found in cow's milk.

Key points

  • There are two types of allergic reactions to milk proteins: reactions involving IgE antibodies (IgE-mediated) and reactions not involving IgE antibodies (non-IgE-mediated). There are also some conditions that include both mixed IgE-mediated and non-IgE-mediated reactions.
  • Non-IgE allergic reactions are the most common milk allergies in infants and children, and they are classified into three categories.
  • All non-IgE-mediated cow’s milk allergies are treated by removing cow’s milk from a child’s diet.
  • Some types of non-IgE-mediated cow’s milk protein allergy are lifelong while others improve over time. Your child's health-care provider can advise how to safely reintroduce cow’s milk protein when your child is ready.
Last updated: July 5th 2024